ILLLI对急性缺血性脑血管病患者血液纤溶功能的影响  

The Effect of ILLLI Therapy on Blood Fibrinolytic Activity in Patients with Acute Ischemic Cerebrolvascular Disease

作　　者：刘颖[1] 徐忠宝[1] 刘筑闻[2] 马宗廉[2] 

机构地区：[1]首都医科大学附属北京友谊医院神经内科,北京100050 [2]首都医科大学生物医学工程系,北京100054

出　　处：《应用激光》1998年第6期280-282,287,共4页Applied Laser

摘　　要：急性ICVD患者，随机分入激光综合治疗组和常规药物组，两组患者均予通脉液500ml.川芎嗪100mg静脉滴注，每天一次，十天为一疗程，激光组同时予ILLLI，波长632.8nm，末端输出功率1.5～2.0mW，每次60分钟，每天一次，十天为一疗程。两组患者均在治疗前后四次取血作纤溶功能动态检测。结果表明，ILLLI具有降低血浆纤维蛋白原含量，降低PAI活性，增强t—PA活性，增加血浆FDP和D—Dimer含量的作用。能够激活患者的纤溶功能.是ILLLII治疗ICVD的机理之一。In the present study, 40 patients with acute ischemic cerebrovascular disease (ICVD) were randomly divided into common used drug group (drug group, 20 cases ) .which was only given dextron 500ml and ligustrazini phosphatis 100mg intravellously once a day totally for 10 days, and laser combined group (laser group, 20 cases), which was given common used drug and intravascular low-level He-Ne laser irradiation (ILLLI) therapy daily for 10 days (each procedure lasted 60 min at output end power of 1. 5-2. 0mW). Activity of fibrinolytic system was performed dynamically in each group. The result showed that ILLLI therapy could decrease plasma fibrinogen contents and PAI activity, increase t - PA activity, FDP and D - Dimer level. Therfore, it showed ILLLI could stimuilate activity of fibrinolytic system, this may be one of mechanisms of ILLLI therapy in the patients with ICVD.

关 键 词：激光血管内照射 缺血性脑血管病 纤溶功能 

分 类 号：R454.2[医药卫生—治疗学] R743.3[医药卫生—临床医学]