囊泡作为药物载体的研究进展  

Progress on Vesicle as Drug Carrier

作　　者：赵静[1] 王仲妮[1] 

机构地区：[1]山东师范大学化学化工与材料科学学院,山东济南250014

出　　处：《食品与药品》2010年第3期129-132,共4页Food and Drug

基　　金：山东省自然科学基金(Y2006B29);贵州省教育厅自然科学研究项目[黔教科(2007)016号]

摘　　要：囊泡有较强的增溶能力,其双层膜具有较好的牢固性和稳定性,作为药物载体给药途径较广,载药稳定性、药物增溶量以及药物生物利用度较高。本文介绍了囊泡作为药物载体的研究现状,包括囊泡形成,膜结构选择和应用,以及囊泡在口服给药、局部给药和体内给药的应用。With significant solubilization and stronger robustness and stability of bilayer, the vesicle as a drug carrier has a series of advantages such as wide administration routes, high stability of drug-loaded and drug solubilization, improved bioavailability of drug. This paper introduces the research on vesicle as a drug carrier, including the formation of vesicle, selection and application of bilayer membrane, and summarizes the applications of vesicle in oral, local and in vivo administration.

关 键 词：囊泡 表面活性剂 药物载体 

分 类 号：R944.5[医药卫生—药剂学]