马来酸二甲酯合成新工艺研究:Ⅱ酯化反应条件研究  

A new process for the synthesis of dimethyl maleate:Ⅱ study on the conditions of esterification

作　　者：王天贵[1] 李强[2] 余锡孟[1] 

机构地区：[1]河南工业大学化学化工学院,河南郑州450001 [2]山西大同大学化学与化工学院应用化学系,山西大同037009

出　　处：《化学工程师》2010年第3期3-6,共4页Chemical Engineer

基　　金：河南省教育厅自然科学研究计划(2008A530001)

摘　　要：本文研究用自制的固体分子筛催化剂催化马来酸酐与甲醇酯化反应合成马来酸二甲酯，目的是研究开发马来酸二甲酯绿色合成新工艺。酯化反应在压力釜内进行，分别考察了反应温度、反应时间、催化剂用量、原料摩尔比等条件对马来酸二甲酯收率的影响。研究结果表明，温度升高有利于马来酸二甲酯的生成，最佳反应温度为105～110℃。适当增加醇酐摩尔配比，延长反应时间和增加催化剂用量均有利于顺丁烯二酸二甲酯的生成，在醇：酐为3：1（摩尔比）、反应时间为12h、H—β沸石用量为0．5％（与顺酐的质量百分比）时，二酯得率达到93．41％。H—β沸石催化剂能够重复使用3次。This article studied using solid molecule sieves as the catalyst of the esterification of methanol and maleic anhydride. The investigation focused on the effects of esterification conditions on both conversion of maleic anhydride and reaction selectivity. Reaction temperature, reaction time, amount of the catalyst and molar ratio of the raw materials were studied. Experimental results indicate that the increase of reaction temperature benefits the production of dimethyl maleate, with the optimum range being 105-110℃. Similarly, increases of the ratio of methanol to maleic anhydride, reaction time and catalyst amount also help the production of the goal ester. With the amount of the catalyst being at 0.5 percent of the maleic anhydride, the ratio of methanol to maleic anhydride being 3：1 and reacting 12h at 110℃, the yield of dimethyl maleate may be over 93%. The catalyst can be reused for three times without substantial efficiency loss.

关 键 词：顺丁烯二酸二甲酯 甲醇 马来酸酐 H—β沸石分子筛 

分 类 号：TQ225.24[化学工程—有机化工]