阿立哌唑治疗老年期精神分裂症的疗效观察  

Comparative study of aripiprazole in treatment of aged schizophrenia

作　　者：伏彩霞 翟歆明 李拉珂 王宝安[1] 

机构地区：[1]宝鸡市康复医院,陕西宝鸡721001

出　　处：《现代医药卫生》2010年第7期1001-1002,共2页Journal of Modern Medicine & Health

摘　　要：目的:比较阿立哌唑和利培酮治疗老年期精神分裂症的疗效和安全性。方法:将60例老年期精神分裂症患者随机分为阿立哌唑组和利培酮组,分别给予阿立哌唑和利培酮治疗8周,采用简明精神病评定量表(BPRS),不良反应量表(TESS)分别评定疗效和不良反应。结果:两组疗效差异无显著性(P>0.05),但阿立哌唑的不良反应较利培酮少而轻微。结论:阿立哌唑治疗老年期精神分裂症疗效好,起效快,不良反应少。Objective：To compare the efficacy and safety of aripiprazole and risperidone in the treatment of aged schizophrenia. Methods： A total of 60 aged schizophrenia were randomized into aripiprazole group and risperidone group, and treated with aripiprazole or risperidone respectively for 8 weeks.Brief Psychiatric Rating Scale （BPRS） was used to assess the clinical efficacy,and Treatment Emergent Symptom Scale （TESS） was used to assess adverse reactions.Results：The effective rate in the aripiprazole and risperidone groups had no stastistical deferences between the two groups （P〉0.05）.The adverse reactions of aripiprazole were mild and less.Conclusion：Aripiprazole for treating aged schizophrenia has faster effect and its side effects are less and milder.

关 键 词：阿立哌唑 利培酮 老年期精神分裂症 疗效 

分 类 号：R5[医药卫生—内科学]