β-族溶血性链球菌感染与胎膜早破  

Infection of β-hemolytic streptococcus and premature rupture of membranes

作　　者：翁秀琴[1] 秦洁[1] 丁香翠[1] 陈利琼[1] 陈翔[1] 李克诚[1] 

机构地区：[1]温州医学院附属三院,浙江温州325200

出　　处：《中国妇幼保健》2010年第9期1250-1251,共2页Maternal and Child Health Care of China

基　　金：温州市科技局立项课题(Y20080225)

摘　　要：目的:探讨β-族溶血性链球菌(GBS)感染与胎膜早破的关系。方法:选择122例未足月胎膜早破(PPROM)孕妇的宫颈-阴道分泌物进行GBS培养,与同期的170例足月胎膜早破(PROM)孕妇和200例正常妊娠孕妇作对照,对GBS阳性的胎膜早破孕妇的羊水做白介素-6(IL-6)测定,并随机选择20例GBS阴性的胎膜早破孕妇作比较。结果:PPROM孕妇宫颈-阴道分泌物GBS阳性率(17.2%)明显高于PROM(11.8%)和正常组(6.0%)(P<0.05),GBS阳性的胎膜早破孕妇羊水IL-6(176.6±82.4)ng/L明显高于GBS阴性的胎膜早破孕妇(122.7±59.3)ng/L(P<0.05)。结论:GBS感染可引起胎膜早破的发生。Objective： To explore the relationship between β - hemolytic streptococcus and premature rupture of membranes （PROM） . Methods： The cervical and vaginal secretion samples of 122 cases with preterm premature rupture of membranes （PPROM） , 170 cases with PROM and 200 normal pregnant women were cultured for β -hemolytic streptococcus, the amniotie fluid samples of PROM women with positive β -hemolytic streptococcus （study group） were collected for IL -6 detection, 20 PROM women without positive β -he- molytic streptococcus were selected randomly and designed as control group. Results ： The positive rate of β - hemolytic streptococcus in cervical and vaginal secretion samples of PPROM women （ 17. 2% ） was significantly higher than those in PROM women （ 11.8% ） and normal pregnant women （6. 0% ） （ P 〈 0. 05 ） ; the IL - 6 level in amniotic fluid samples of study group [ （ 176. 6 ± 82.4） ng/L] was significantly higher than that of control group [ （ 122. 7 ±59. 3 ） ng/L] （P 〈 0. 05 ） . Conclusion： Infection of β - hemolytic streptococcus may cause the occurrence of PROM.

关 键 词：胎膜早破 β-族溶血性链球菌 白介素-6 

分 类 号：R714.433[医药卫生—妇产科学]