徐州地区1572例健康人群骨密度和骨质疏松症调查  

Investigation of bone mineral density and osteoporosis in 1572 healthy people in Xuzhou

作　　者：汪明星[1,2] 房明亮[1] 王建强[1] 朱自强[1] 

机构地区：[1]苏州大学医学院在职博士班,江苏苏州215123 [2]徐州医学院第二附属医院骨科,江苏徐州221006

出　　处：《徐州医学院学报》2010年第3期167-170,共4页Acta Academiae Medicinae Xuzhou

基　　金：徐州市科委资助课题(X2005235)

摘　　要：目的通过测量徐州地区健康人群骨密度（BMD），分析骨密度的变化规律及骨质疏松症的发病率，提高对骨质疏松症诊断的可靠性，为骨质疏松症的防治提供参考依据。方法采用GE-LUNAR公司生产的双能X线骨密度仪对徐州地区2005～2008年1572例健康人进行BMD测定，分别做股骨上端及第2～4腰椎椎体测量，并按5岁为一个年龄组分组。以峰值BMD减低2．5SD为诊断骨质疏松症标准，按性别、年龄分组进行统计学分析。结果徐州地区女性BMD峰值则在30～35岁，男性在35岁左右，女性55岁后骨量下降较男性显著，骨质疏松发病率女性高于男性。结论对于55岁女性和65岁男性，之前应加强普及骨质疏松预防知识，之后同时采取相应干预措施，以减少骨质疏松症的发生，为徐州地区骨质疏松症的诊治提供参考依据。Objective To analyze the variations of bone mineral density （BMD） and the incidence of osteoporosis by means of BMD measurements in healthy population in Xuzhou so as to improve the accuracy of osteoporosis diagnosis and provide reference for the prophylaxis and treatment of osteoporosis. Methods BMD determination by dual energy X -ray absorptiometry （DEXA） and measurements of the femur neck and lumbar vertebrae （2 -4 ） were conducted in 1572 healthy people who were grouped at a 5 - year age interval. An increase by 2.5 SD from the BMD peak was designated the criterion for osteoporosis diagnosis and statistical analysis in gender and age groups. Results The BMD peak occurred between 30 and 35 years of age in women and declined afterwards, whereas at around 35 years of age in men. A remarkable decrease in BMD was shown in women as of 55 years of age. The female groups had higher osteoporosis inci- dence than the male groups. Conclusion Popularization of the awareness of the prophylaxis and treatment of osteoporosis should be enhanced for women before 55 and men before 65, while for the subsequent years, relevant interventions should be taken to reduce the osteoporosis incidence.

关 键 词：骨质疏松症 骨密度 骨峰值 徐州 

分 类 号：R681[医药卫生—骨科学]