良、恶性妊娠滋养细胞肿瘤的MRI特征分析  

Analysis of the characteristics of MRI in benign and malignant gestational trophoblastic neoplasia

作　　者：陈伟[1] 严志汉[1] 方必东[1] 虞志康[1] 陈裕[1] 张弦[1] 白光辉[1] 曾庆娟[1] 

机构地区：[1]温州医学院附属第二医院育英儿童医院放射科,浙江温州325027

出　　处：《温州医学院学报》2010年第1期49-52,共4页Journal of Wenzhou Medical College

基　　金：温州市科技局科技计划资助项目(Y20080040)

摘　　要：目的:分析良、恶性妊娠滋养细胞肿瘤(GTN)的MRI平扫及动态增强特征。方法:回顾性分析21例(10例良性、11例恶性)经病理证实的GTN临床和MRI资料,所有病例均行MR常规扫描,其中16例行MR动态增强扫描。结果:病灶位于子宫腔或子宫肌层内,其共同MRI表现包括:①子宫增大,子宫腔内见"蜂窝状"或团块状异常信号影,在T1WI呈等或混杂信号,在T2WI呈混杂高信号;②9例子宫旁和肌层内可见扭曲、扩张的血管影,在MR动态增强扫描上显示更清晰。其不同MRI表现为:良性GTN的子宫肌层无受累,恶性者子宫肌层常受侵,表现为肌层的连续性中断,动态增强扫描有助于清晰显示病灶。结论:MRI平扫及其增强扫描对于良恶性妊娠滋养细胞肿瘤的定位、定性诊断具有较高的参考价值,可以为临床诊断及治疗随访提供重要信息。Objective：To analyze the conventional MR scan and dynamic contrast-enhanced scan features of benign and malignant gestational trophoblastic neoplasia（GTN）.Methods：The clinical and MRI findins of 21 cases（benign 10 case and malignant 11 cases） of GTN which proved by pathology were retros pectively reviewed,all the patients underwent MR scaning,16 of 21 cases underwent dynamic contrast-enhanced MR scaning.Results：The lesions mainly located in the cavity of uterus or myometrium,the general MR imaging characteristics of benign and malignant GTN including：①Hysterauxesis or characteristic honeycomb-like or crumb mass in the uterine cavity,which showed hypo-intensity or iso-intensity on T1WI and mixed hyper-intensity on T2WI;②Tortuous dilation of myometrial and para-uterine vessels were detected in 9 cases of 21,which displayed more clearly on MR dynamic-enhanced scaning.The different characteristics of benign and malignant GTN including：The myometrium was not invaded in benign GTN,in contrast,it was usually invaed in malignant GTN,and the dynamic contrast-enhanced scan was helpful to display the lesions clearly.Conclusion：Conventional MR scan and dynamic contrast-enhanced scan have considerable value in level of diagnosis and qualitative diagnosis of benign and malignant GTN.It also can provide valuable information for clinical diagnosis and follow-up therapy.

关 键 词：妊娠滋养细胞肿瘤 磁共振成像 诊断技术和方法 

分 类 号：R445.2[医药卫生—影像医学与核医学]