复方公英片质量标准的研究  

Study on the Establishment of the Quality Standard of Fufanggongying Tablets

作　　者：植达诗 牟晓崟 袁遥 

机构地区：[1]广西玉林食品药品检验所,玉林537000

出　　处：《中国药事》2010年第3期280-282,共3页Chinese Pharmaceutical Affairs

摘　　要：目的建立复方公英片中板蓝根、蒲公英的薄层鉴别方法及板蓝根中腺苷的高效液相含量测定方法。方法采用Agilent C18色谱柱;流动相为甲醇-0.5%三乙胺溶液（8∶92）;流速为1.0mL.min-1;检测波长为260nm;柱温为25℃。结果腺苷在1.021~30.63μg范围内呈良好的线性关系,r=0.9994,平均回收率96.48%,RSD为1.18%（n=6）。结论该方法操作简便,重复性好,结果准确可靠,适用于该药的质量控制。Objective To identify Radix Isatidis and Herba Taraxaci by TLC method and to determine adenosine in Fufanggongying Tablets by HPLC.Methods Using Agilent C18 column,methanol-0.5% triethylamine（8∶92） was mobile phase with the flow rate of 1.0mL·min-1.The detectve wavelength was 260nm and the column temperature was 25℃.Results The linear range of adenosine was 1.021～30.63μg（r=0.9994）.The average recovery rate was 96.48% with RSD as 1.18%（n=6）.Conclusion The method is simple,accurate and reliable.It can be used in the quality control of crude drug.

关 键 词：HPLC 复方公英片 腺苷 

分 类 号：R284[医药卫生—中药学] R927.2[医药卫生—中医学]