蒙古族人群病原体感染与高血压患病关系  

Relationship between pathogenic infection and hypertension in Mongolian

作　　者：唐惠[1,2] 王艾丽[1] 白双链[3] 刘丽娟[4] 佟伟军[1] 张永红[1] 

机构地区：[1]苏州大学医学部放射医学与公共卫生学院流行病学教研室,江苏苏州215123 [2]上海市杨浦区疾病预防控制中心 [3]内蒙古科左后旗疾病预防控制中心 [4]中国人民解放军军事医学科学院微生物与流行病学研究所病原与生物安全国家重点实验室

出　　处：《中国公共卫生》2010年第3期295-296,共2页Chinese Journal of Public Health

基　　金：国家自然科学基金(30471484)

摘　　要：目的探讨肺炎衣原体、肺炎支原体、幽门螺旋杆菌和柯萨奇病毒感染与高血压的关系。方法在蒙古族人群高血压现况研究基础上,选择767例高血压患者和762名血压正常者,进行病例对照研究;对研究对象有关危险因素进行问卷调查和身体指标测量,进行血脂、血糖、肺炎衣原体、肺炎支原体、幽门螺旋杆菌和柯萨奇病毒IgG抗体检测。结果病例组肺炎衣原体(40.6%)、肺炎支原体(18.3%)、幽门螺旋杆菌(56.3%)和柯萨奇病毒(41.4%)IgG抗体阳性率均分别高于对照组肺炎衣原体(36.8%)、肺炎支原体(18.0%)、幽门螺旋杆菌(53.0%)和柯萨奇病毒(40.9%)IgG抗体阳性率,但差异均无统计学意义(P>0.05);在调整心血管危险因素后,肺炎衣原体、肺炎支原体、幽门螺旋杆菌和柯萨奇病毒感染对高血压患病危险性影响差异均无统计学意义。结论肺炎衣原体、肺炎支原体、幽门螺旋杆菌、柯萨奇病毒感染与高血压危险性无明显关联。Objective To explore the relationship between Chlamydia pneumoniae（CP）,Mycoplasma pneumonia（MP）,Helicobacter pylori（HP） and Coxsackie virus（CV） infection and hypertension.Methods On the basis of prevalence survey for hypertension in a Mongolian population,767 hypertensives and 762 normotensives were selected as subjects to conduct a case-control study.The body indexes of the subjects were measured,and blood lipid,blood glucose,IgG antibo-dies of CP,MP,HP,and CV were examined for all subjects.Results The positive rates of IgG antibodies of CP（40.6%）,MP（18.3%）,HP（56.3%）,and CV（41.4%） in the cases were higher than the positive rates of IgG antibodies of CP（36.8%）,MP（18.0%）,HP（53.0%）,and CV（40.9%） in the controls.But the differences were not statistically significant（P0.05）.After adjustment for confounding factors,ORs of hypertension related to CP,MP,HP,and CV infection were not statistically significant（P0.05）.Conclusion CP,MP,HP,and CV infections are not associated with hypertension.

关 键 词：高血压 病原体感染 危险因素 

分 类 号：R117[医药卫生—公共卫生与预防医学] R544.1