不同年龄段非瓣膜病心房纤颤的临床特点与预后分析  

Clinical Features and Prognosis of Nonvalvular Atrial Fibrillation in Different Age Stages

作　　者：曾敏[1] 吴智勇[1] 郑茵[1] 陈娟[1] 冯光球[1] 符秀虹[1] 

机构地区：[1]海南省海口市人民医院医疗康复中心二区,570311

出　　处：《中国全科医学》2010年第7期790-791,共2页Chinese General Practice

摘　　要：目的了解各年龄段非瓣膜病心房纤颤(NVAF)患者的病因分布,脑卒中发生率以及心房纤颤类型对脑卒中的影响。方法对329例NVAF患者进行随访调查。按年龄分为A组(≤60岁)、B组(61～70岁)、C组(71～80岁)、D组(>80岁)4组,调查各组的临床特点及预后。结果NVAF各年龄组患者的首要病因均为冠心病;A、B组的甲状腺机能亢进性心脏病的病因构成均明显高于C、D组(P<0.05)。各年龄组患者的脑卒中发生率分别为21.79%、26.61%、35.85%和50.00%,脑卒中发生率有随年龄增长而增加的趋势(P<0.05)。对不同NVAF患者的缺血性脑卒中发生率按年龄因素进行分层分析,仅A组有统计学意义(P<0.05)。结论冠心病是NVAF各年龄组的首要病因;脑卒中的发生随年龄的增加而增长;持续性和阵发性心房纤颤类型在年龄≤60岁的年龄组患者脑卒中发生率间有明显差异。Objective To explore the incidence of stroke and relative factors in patients of different age groups with non-valvular atrial fibrillation（NVAF）.Methods Totally 329 NVAF patients admitted in our hospital from January 1999 to December 2001 were divided into four groups according to their ages：group A （≤60 years）,group B （61 -70 years）,group C （71 -80 years）,and group D （﹥80 years）.The etiology,clinical features and prognosis of all four groups were investigated and summarized.Results Coronary heart disease （CHD） remained the leading cause in all groups.Hyperthyroid heart disease accounted a significantly higher proportion in groups A and B than in groups C and D（P0.05）.The incidence of stroke was 21.79%,26.61%,35.85%,and 50.00% in groups A,B,C,and D,respectively.It increased along with the increase of age （P0.05）.The incidence of ischemic stroke were significantly different among different NVAF type strata （P0.05） in group A,while no such difference was observed in other three groups （P0.05）.Conclusion CHD is the main cause of NVAF.Incidence of stroke increases with aging.The incidences of Persistent and paroxysmal atrial fibrillation only differ among NVAF patients younger than 60 years.

关 键 词：非瓣膜病心房纤颤 卒中 发病年龄 

分 类 号：R541.75[医药卫生—心血管疾病]