A new insight into cattle's maternal origin in six Asian countries  

作　　者：Shangang Jia Yan Zhou Chuzhao Lei Ru Yao Zhiying Zhang Xingtang Fang Hong Chen 

机构地区：[1]College of Animal Science and Technology, Northwest A & F University, Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling 712100, China [2]Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China [3]Graduate University of Chinese Academy of Sciences, Beijing 100094, China [4]State Key Laboratory of Cognitive Neuroscience and Learning (Beijing Normal University), Beijing 100875, China [5]Institute of Cellular and Molecular Biology, Xuzhou Normal University, Xuzhou 221116, China

出　　处：《Journal of Genetics and Genomics》2010年第3期173-180,共8页遗传学报（英文版）

基　　金：supported by Chinese National Scientific Fund (No.30972080 and 30771544);the National 863 Program of China (No.2006AA10Z197 and 2008AA101010);National Key Technology R&D Program (No.2006BAD01A10-5);the Project of Measurement of Genetic Distances Among Chinese Indigenous Bovine Breeds (Chinese Agricultural Finance Department [2002] No.9);Keystone Project of Transfergene in China (No.2009ZX08009-157B and 2008ZX08007-002);"13115" Sci-Tech Innovation Program of Shaanxi Province (No.2008ZDKG-11);Program of National Beef Cattle Industrial Technology System,Basic and Foreland Technology Study Program of Henan Province (No.072300430160);Natural Science Foundation of Xuzhou Normal University (No.2003XY234)

摘　　要：The domestication of cattle fuelled the development of agricultural society in the history of human being. The evolution and genetic relationship of cattle can be elucidated by investigating the variation of mitochondrial DNA （mtDNA） D-loop sequence. In this study, we built a cattle phylogeny with a pool of 856 individual D-loop sequences, of which 264 Chinese cattle D-loop sequences were obtained in this study （141 ones were first analyzed, and 123 were first submitted） and the rest sequences of cattle from six Asian countries （Japan, Korea, Mongolia, Nepal, India and China） were retrieved from GenBank. Our results indicated that cattle from six Asian eounlries fell into three clades, Bos taurus （taurine）, Bos indicus （zebu） and yak. Four main haplogroups T1A, T2, T3 （including T3A and T3B） and T5 were found in taurine, and two haplogroups I1 and 12 in zebu. Furthermore, we found that I1 and 12 haplogroups were separated by four variable sites rather than five ones and four haplogroups or sub-haplogroups of T1A, T3A, T3B and T5 were found for the first time in these Asian cattle. These data brought us a new insight into cattle＇s genetic structure in these six Asian countries. The geographical distribution of haplogroups was also outlined to provide systematic information on cattle genetic resources.The domestication of cattle fuelled the development of agricultural society in the history of human being. The evolution and genetic relationship of cattle can be elucidated by investigating the variation of mitochondrial DNA （mtDNA） D-loop sequence. In this study, we built a cattle phylogeny with a pool of 856 individual D-loop sequences, of which 264 Chinese cattle D-loop sequences were obtained in this study （141 ones were first analyzed, and 123 were first submitted） and the rest sequences of cattle from six Asian countries （Japan, Korea, Mongolia, Nepal, India and China） were retrieved from GenBank. Our results indicated that cattle from six Asian eounlries fell into three clades, Bos taurus （taurine）, Bos indicus （zebu） and yak. Four main haplogroups T1A, T2, T3 （including T3A and T3B） and T5 were found in taurine, and two haplogroups I1 and 12 in zebu. Furthermore, we found that I1 and 12 haplogroups were separated by four variable sites rather than five ones and four haplogroups or sub-haplogroups of T1A, T3A, T3B and T5 were found for the first time in these Asian cattle. These data brought us a new insight into cattle＇s genetic structure in these six Asian countries. The geographical distribution of haplogroups was also outlined to provide systematic information on cattle genetic resources.

关 键 词：D-LOOP ASIA maternal origin MTDNA 

分 类 号：Q343.1[生物学—遗传学] TQ247.56[化学工程—有机化工]