食品及公共场所从业人员血清乙肝标志物、肝功能检测分析  

Analysis of HBsAg,HBeAg,ALT of employees in food and public industry

作　　者：钟有光 李达森 彭美薇 梁炳健[1] 冼桂江 

机构地区：[1]广西梧州市疾病预防控制中心,广西梧州543002

出　　处：《中国卫生检验杂志》2010年第2期365-366,378,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的：了解梧州市食品及公共场所从业人员乙肝病毒感染状况，为卫生监督及乙肝防控提供依据。方法：取受检者静脉血，酶联免疫吸附试验（ELISA）测乙肝表面抗原（HBsAg）、e抗原（HBeAg），改良赖氏法测血清丙氨酸氨基转移酶（A坍）。结果：2005～2008年度参加体检的食品、公共场所从业及其岗前体检人员共71512人，HBsAg、HBeAg总阳性率分别为6．31％、1．55％，HBeAg占HBsAg阳性总比率为24．64％；3种检出率均呈逐年下降趋势且有统计学意义。年龄问检出率呈低年龄组向高年龄组逐一降低趋势，性别检出率男高于女，且年龄组间、性别间差异均有统计学意义。ALT总异常率0．28％；异常率年间波动在0．23％～0．37％之间，无统计学差异意义；而性别间，不同感染模式、无感染者之间，差异均具统计学意义。结论：乙肝病毒感染，尤其HBeAg阳性，对健康及作为传染源有很大的危险性，应予高度关注与重视。Objective：To investigate the epidemiology of hepatitis B virus infection among the employee in food and public industry of Wuzhou City,and provide guideline for the sanitary supervision on the hepatitis B control.Methods：Use ELISA to detect HBsAg and HBeAg,and use improved Beitman′s method to measure ALT.Results：Among the 71512 cases,the positive rates of HBsAg were 6.31%,and HBeAg 1.55% respectively.Furthermore,in the HBsAg positive cases,24.64% are HBeAg positive.The annual positive rate of HBsAg,HBeAg and HBeAg/HbsAg,all declined year by year while the younger group has lower positive rate than the elder age group,and female lower than male,all with great statistical significance.The total ALT abnormal rate is 0.28% and annual ALT abnormal rate fluctuated between 0.23%-0.37%.In generally,the elder group has lower rate but with no significance.However,there are different significances between the male and female（male 0.48%.female 0.16%） in ALT abnormal.The ALT abnormal has different significances that HBsAg positive group（1.09%）,HBeAg positive group（5.31%） have much higher rate than non-infected group（0.15%）.Conclusion：Hepatitis B virus-carrier,especially those with HBeAg positives,have great risk to public health as source of infection,should be paid more attention to.Physical examinations,tableware disinfection,vaccine inoculation to the high-risk people,combined with hygienic propaganda,all are effective measures to reduce the hepatitis B infection.

关 键 词：食品及公共场所从业人员 HBSAG HBEAG ALT 感染模式 

分 类 号：R512.62[医药卫生—内科学]