中药复方清脑胶囊应用超临界流体萃取技术的探讨  

Research and Development of QingNao Capsule of TCM Using the SFE Technique

作　　者：侯晋军[1] 姚帅[1] 呼海涛[1] 笪娟[1] 龙华丽[1] 杨洲[1] 蔡录影[1] 吴婉莹[1] 果德安[1] 

机构地区：[1]中国科学院上海药物研究所中药现代化研究中心,上海201203

出　　处：《世界科学技术-中医药现代化》2010年第1期89-93,共5页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：上海市科委中药现代化专项(07DZ19711):颜氏清脑2号方治疗脑梗塞临床与实验研究;负责人:吴婉莹

摘　　要：本文通过分析清脑胶囊的研发历程,探讨超临界技术对新药研发过程中各环节的影响和可能产生的问题,并结合清脑胶囊的实例,给出解决的对策,为超临界流体萃取技术应用于中药新药开发提供可资借鉴的参考。The Supercritical Fluid Extraction （SFE） technique has been used in Traditional Chinese Medicine （TCM） , but some handicaps still remain in the research and development （R＆D） of new drugs of TCM, especially when more plants are comprised. Through reviewing the R＆D progress of QinNao Capsule, the impacts and potential problems caused by the SFE technique in the R＆D of new drugs are discussed, and possible scenarios are put forward.

关 键 词：超临界流体萃取 中药 新药 川芎 羌活 

分 类 号：R284.2[医药卫生—中药学]