葛根芩连丸中多糖类溶出度的测定方法  

Determination of Polysaccharides Dissolution in Gegenqinlian Pills

作　　者：马兰兰[1] 陈天朝[2] 周欢欢[1] 翟来超[1] 

机构地区：[1]河南中医学院,河南郑州450008 [2]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2010年第2期258-259,共2页Acta Chinese Medicine

摘　　要：目的:建立测定葛根芩连丸中多糖类溶出度的方法。方法:溶出度的测定用蒽酮硫酸法显色,紫外可见分光光度法在622nm处测定吸光度。结论:多糖的溶出度在45min内达到了70%的标准。结果:测定葛根芩连丸中多糖溶出度的方法简单,可为葛根芩连丸质量评价的研究提供新的参考指标,也为复方制剂中多糖类的含量测定提供参考。Objective：To establish the determination method of polysaccharide dissolution in the Gegenqinlian pills.Methods：Using anthrone-sulfuric acid method to color,absorbance was measured at 622 nm by UV-visible spectrophotometry.Results：The dissolution of polysaccharides in 45 min reached the standard of 70%.Conclusion：The determination of polysaccharide dissolution in Gegenqinlian pill method is simple and it can provide a new reference index Benchmark for the study of quality standards of Gegenqinlian pills,but also provide a reference for the determination of polysaccharides in compound preparation.

关 键 词：葛根芩连丸 多糖 蒽酮硫酸法 溶出度 

分 类 号：R284[医药卫生—中药学]