小型猪上颌窦内提升穿破上颌窦粘膜同期植入种植体的骨结合情况的研究  

Experimental study of the osseointegration of dental implants after osteotome maxillary sinus elevation in mini-pigs with maxillary sinus mucosa perforation

作　　者：刘刚利[1] 马跃[1] 邵山[2] 徐欣[1] 

机构地区：[1]山东大学口腔医学院,济南250012 [2]济南市第三人民医院,济南250101

出　　处：《山东大学耳鼻喉眼学报》2010年第1期67-70,共4页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：山东省自然科学基金项目(Y2008C107)

摘　　要：目的观察上颌窦内提升术中窦底粘膜穿通对同期植入的种植体骨结合的影响,以及生物膜的应用效果。方法试验用小型猪3只,X线确定上颌窦底位置,全麻下拔除小型猪双侧上颌相应位置的牙,6个种植位点随机分为3组,实验A组穿破窦底同期植入种植体,实验B组穿破窦底粘膜加生物膜同期植入种植体,对照组窦底粘膜完整。术后6个月观察大体标本,做X线检查,做带种植体的骨磨片,观察种植体的骨结合情况及窦底的愈合情况。结果大体标本显示种植体无松动,A组种植体暴露在上颌窦内,B组与对照组窦底粘膜完整。X线显示3组的种植体周围的骨质均匀,没有阴影。骨磨片镜下观察骨结合情况,3组没有差别。结论上颌窦底粘膜的穿通对种植体骨结合没有影响,窦底粘膜穿通后加生物膜有利于窦底粘膜的愈合。Objective To observe the osseointegration of dental implants embedded in mini-pigs after osteotome maxillary sinus elevation with maxillary sinus mucosa perforation, and the effect of the biological membrane. Methods In this study, 6 BLB dental implants were placed in 3 mini pig＇s bilateral postmaxilla. The 6 implant places were randomly divided into three groups： ①group A： the maxillary sinus mucosa was broken and placement was simultaneously implanted;②group B： the maxillary sinus mucosa was broken and placement was synchronously implanted and membranes added ;③control group： the maxillary sinus mucosa was not broken. The animals were sacrificed 6 months postoperative, digital panoramic examination was used and the postmortem specimens were examined grossly and histologically. Results There was no difference between the control group and the experimental groups, and no significant difference between group A and group B. Conclusions Maxillary sinus mucosa perforation does not affect the osseointegration of the implant.

关 键 词：上颌窦内提升 牙种植 骨结合 小型猪 

分 类 号：R276.8[医药卫生—中医五官科学]