尼莫地平在外伤性脑肿胀中的治疗体会  

Experience of Nimodipine in the Treatment of Acute Traumatic Brain Swelling

作　　者：周振国[1] 畅涛[1] 康瑞刚[1] 赵晓平[1] 范晓璇[1] 柏鲁宁[1] 周雄波[1] 王更新[1] 

机构地区：[1]陕西中医学院附属医院神经外科,陕西西安712000

出　　处：《辽宁中医药大学学报》2010年第4期172-173,共2页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:观察总结尼莫地平在治疗急性外伤引起脑肿胀的临床疗效。方法:对2007年4月—2009年4月治疗的44例经头颅CT证实的外伤性脑肿胀病人,随机分为尼莫地平治疗组和对照组进行观察,治疗前后比较两组病人的蛛网膜下腔出血、脑肿胀程度,脑挫裂伤水肿体积及神经功能缺损评分差。结果:尼莫地平组较对照组蛛网膜下腔出血吸收、脑肿胀程度,脑挫裂伤水肿体积及神经功能缺损评分差疗效均非常明显(P<0.05),且应用尼莫地平愈早,效果愈明显。结论:尼莫地平早期治疗急性外伤引起脑肿胀可明显改善病情及预后。Objective： The observation and summary of nimodipine in the treatment of acute traumatic brain swelling caused by the clinical efficacy. Methods： April, 2007 - April ,2009 of 44 cases treated by cranial CT confirmed traumatic brain swelling were randomly divided into nimodipine treatment group and control group to observe and compare the patients in araehnoids under the hemorrhage, brain swelling degree of cerebral contusion edema volume and neurological deficit score difference before and after treatment. Results： Compared with group, the nimodipine group manifests significant effect in absorption of subarachnoid hemorrhage, brain swelling degree of cerebral contusion edema volume and neurological deficit score （ P〈0.05 ） than the control group, and the sooner the application of nimodipine, the clearer the effect. Conclusion： Early treatment of nimodipine in acute traumatic brain swelling can significantly improve the condition and prognosis.

关 键 词：尼莫地平 脑肿胀 脑水肿 治疗 

分 类 号：R64[医药卫生—外科学]