人细小病毒B19的特性及其与血浆蛋白制品的相关性  

Character of Human Parvovirus B19 and Its Relationship to Plasma Protein Products

作　　者：卜凤荣[1] 孙捷[2] 李志军[3] 

机构地区：[1]军事医学科学院野战输血研究所,北京100850 [2]河北大安制药有限公司,石家庄050011 [3]河北医科大学科技总公司,石家庄050018

出　　处：《中国生物制品学杂志》2010年第3期329-332,共4页Chinese Journal of Biologicals

摘　　要：人细小病毒B19(B19病毒)是一种直径约为20～25nm的无包膜单链线状DNA病毒,属于细小病毒家族。B19病毒对人类骨髓细胞,特别是红系祖细胞有高度趋向性,易感人群感染B19病毒可引起多种严重疾病,一般通过呼吸道和母婴垂直传播,但通过输注血液和血浆蛋白制品传播也非常普遍,已引起人们的广泛关注。本文对B19病毒的特性及其与血浆蛋白制品的相关性作一综述。Human parvovirus B19 is a 20～25 nm non-enveloped single-strand DNA virus which belongs to the family of parvovirus.B19V has high tropism to bone marrow cells,particularly to the erythroid progenitors.The infection of B19 virus in susceptive individuals may cause a variety of serious illnesses.B19V is generally transmitted via respiratory route or vertically from mother to infant.However,B19V is frequently transmitted through blood or plasma products,which has been paid close attention widely.This paper reviews the progress in research on the character of B19 virus and its relationship to plasma protein products.

关 键 词：人细小病毒B19 P-抗原 血浆蛋白制品 

分 类 号：R373[医药卫生—病原生物学]