血小板去除术联合药物治疗原发性血小板增多症的疗效分析  

Effectiveness of platelet phoresis combined with chemotherapy for the treatment of essential thrombocythemia

作　　者：黎儒青[1,2] 王甜甜[1,2] 叶延瑶[1,2] 赵树铭[1,2] 

机构地区：[1]第三军医大学西南医院输血科 [2]中国人民解放军重庆血站,重庆400038

出　　处：《中国输血杂志》2010年第2期110-112,共3页Chinese Journal of Blood Transfusion

摘　　要：目的探讨血小板去除术联合羟基脲、a-干扰素等药物治疗原发性血小板增多症的临床疗效及预后评价。方法对43名血小板增多症患者采用血小板去除术1—4次后,立即给予羟基脲和a-干扰素等药物治疗。结果血小板去除术后,患者外周血中血小板计数明显下降,临床症状好转,再经羟基脲、a-干扰素等药物联合治疗,所有患者病情均得到明显改善。结论血小板去除术联合羟基脲、a-干扰素治疗血小板增多症有显著疗效。Objective To observe the effect of platelet phoresis combined with drug treatment on essential thrombocythemia（ET）.Methods All patients were treated by platelet phoresis,followed by hydroxyurea and INF-a.Results After platelet phoresis,the platelet counts of patients decreased significantly and the symptoms associated with thrombocythemia improved.Conclusion Platelet phoresis in combination with hydroxyurea and INF-a has a significant effect on ET.

关 键 词：血小板增多症 血小板去除术 羟基脲 A-干扰素 

分 类 号：R457.1[医药卫生—治疗学] R331.143[医药卫生—临床医学]