薄芝注射液对肾小球肾炎影响的临床观察(英文)  

CLINICAL OBSERVATION OF EFFECT OF GANODERMA CAPENSE(GC) ON GLOMERULONEPHRITIS

作　　者：李世宁[1] 吕廉捷[1] 杨燕玲[2] 贺庆芳[3] 李友云 马跃荣[1] 胡礼振[1] 

机构地区：[1]泸州医学院病理学教研室,646000 [2]泸州医学院电镜室,646000 [3]泸州医学院附属医院肾内科,646000

出　　处：《泸州医学院学报》1998年第3期244-250,共7页Journal of Luzhou Medical College

摘　　要：目的；薄芝注射液对肾小球肾炎影响的临床观察。方法：从肾功能、血生化和肾活检光镜、电镜和免疫荧光视察中药薄芝注射液对42例肾小球肾炎患者的治疗作用。结果：结果表明：薄芝注射液可使尿蛋白排出量显著减少，血浆白蛋白逐渐升高，免疫荧光强度明显减弱，上皮下（或内皮下）电子致密沉积物数目减少或消失以及基底膜明显变薄。治疗组42例，显效20冽（47．62％），有效13例（30．95％），无效5例（11．91％），总有效率78．57％，与对照组总有效率81．41％比较无显著性差异（P＞0．05）。结论：研究表明中药薄艺注射液对肾小球肾炎有明显治疗作用。Objative: To investigate the therapeutic effects of GC on glomerulonephritis. Method: The therapeutic effects of GC on 42 glomerulonephritis cases were observed and assessed in terms of renal functions,blood biochemical examinations LM、 EM and immunofluorescence microscopy of renal biopsies. Results: GC could remarkably reduce the excretion of proteinuria, and gradually increase the plasma albumin .The intensity of immunofluorescence diminished obviously, and the number of subepithelial (or subendothelial) electron dense deposits dripped significanily or even disappeard. Of 42 patients of the CC group, 20 were effective(47.63% ), 13 markedly effective (30. 95% ), 5 ineffective(11. 91 % ), and the total effective rate was 78. 57%,which showed no significant difference (P > 0. 05 ) compared with the control group(81. 41 % ). Conclusion:This investigation showed that GC has obvious therapeutic effects on glomerulonephritis.

关 键 词：肾小球肾炎 中医药疗法 薄芝注射液 

分 类 号：R277.523.1[医药卫生—中医学]