2,5-二[(2-羟乙基)氨基]-1,4-苯醌合成的新方法  

A NEW METHOD FOR SYNTHESIS OF 2,5-BIS[(2-HYDROXYETHYL)AMINO]BENZO-1,4-QUINONE

作　　者：王建[1] 刘玮炜[1] 马卫兴[1] 尹福军[1,2] 许兴友[2,3] 陆路德[2] 

机构地区：[1]淮海工学院,江苏连云港222005 [2]南京理工大学,江苏南京210094 [3]淮阴工学院,江苏淮安223003

出　　处：《精细石油化工》2010年第2期8-12,共5页Speciality Petrochemicals

基　　金：江苏省教育厅自然科学基金资助项目(08KJB1 50002);江苏省"六大人才高峰"项目(07-A-024);连云港市科技攻关计划项目(CG0803-2);淮海工学院博士科研启动项目(KQ09006);自然科学课题(Z2009018)

摘　　要：实验以姜黄素和乙醇胺为原料,于45℃回流2 h,得到紫红色产物2,5-二[(2-羟乙基)氨基]-1,4-苯醌,产率约2.6%。经单晶培养和IR、NMR、MS及单晶X衍射等方法对产物进行了确证,并对该新反应机理进行了初步分析。2,5-Bis [（2-hydroxyethyl） amino] benzo-1, 4-quinone was synthesized with Curcumin and ethanolamine as the raw materials to reflux under the temperature of 45 ℃ for 2 h. The product was purplish red and characterized by IR, NMR, MS and single crystal X-ray diffraction. The mechanism of this novel reaction was initially investigated, which laid a foundation for further improvement to the synthesis method.

关 键 词：2 5-二(2-羟乙基)氨基]-1 4-苯醌 姜黄素 乙醇胺 合成 结构 机理 

分 类 号：TQ244.6[化学工程—有机化工]