血尿酸水平与急性脑梗死相关性分析  

Correlation analysis of Serum uric acid level and acute cerebral infarction

作　　者：韩冰[1] 宋利春[1] 

机构地区：[1]中国医科大学附属盛京医院神经内科,辽宁沈阳110004

出　　处：《中国微生态学杂志》2010年第3期270-271,共2页Chinese Journal of Microecology

摘　　要：目的探讨血尿酸水平与急性脑梗死发病及预后的关系。方法检测129例急性脑梗死患者与120例健康组的血尿酸水平及相关指标进行比较,分析其相关性。结果急性脑梗死患者血尿酸水平及异常率明显增高,与对照组之间差异存在非常显著性(P<0.01),在急性脑梗死患者中,血尿酸异常组高血压、高血糖、高血脂及高纤维蛋白原血症的发生率比正常组明显增高,血尿酸异常组较正常组入院第21天神经功能缺损的程度差异存在非常显著性(P<0.01)。结论血尿酸水平与急性脑梗死的发病密切相关,是预后不良的预测因素。Objective To investigate the correlation between serum uric acid levels in patients with acute cerebral infarction and prognosis. Method 129 cases of acute cerebral infarction and 120 healthy people were detected and compared for their serum uric acid levels and related indicators, and the correlation were analyzed. Result The abnormal rate and levels of serum uric acid in patients with acute cerebral infarction were significantly higher than those in control group and the differences were significant （P 〈0.01 ）. In patients with acute cerebral infarction, the group with abnormal serum uric acid had significantly higher incidence rates of hypertension, high blood sugar, high blood lipids and hyperfibrinogenemia than the normal group. The extent of neurological impairment in abnormal serum uric acid group, 21 days after admission, was significantly different with that in normal group （ P 〈 0.01 ）. Conclusion Serum uric acid level is closely related to the pathogenesis of acute cerebral infarction and can be used as a predictor of poor prognosis.

关 键 词：脑梗死 血尿酸 

分 类 号：R711.74[医药卫生—妇产科学]