鲍曼不动杆菌感染的临床分布及耐药性监测  

Clinical distribution and surveillance of drug resistance on Acinetobacter baumannii infection

作　　者：喻长法[1] 叶丽君[1] 郑英姿[1] 段达荣[1] 解晶[1] 

机构地区：[1]浙江省台州市第一人民医院检验科,浙江台州318020

出　　处：《中国卫生检验杂志》2010年第3期592-593,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的：了解鲍曼不动杆菌的临床分布及其对常用抗生素的耐药情况,以指导临床合理用药。方法：回顾2006年1月～2008年12月自临床标本中分离的鲍曼不动杆菌,分析其药敏结果。结果：共检出472株鲍曼不动杆菌,在临床标本中,痰液分布率最高,占70.34%,感染分布以ICU为主,占32.84%,对14种常用抗生素的耐药率除亚胺培南、美洛培南和头孢哌酮/舒巴坦较低外,另11种抗生素的耐药率均较高。结论：鲍曼不动杆菌对亚胺培南、美洛培南和头孢哌酮/舒巴坦较敏感,临床应合理应用抗生素,减少耐药株的产生。Objective：To investigate the clinical distribution and the drug resistance of Acinetobacter baumannii to provide guidance for clinical medication.Methods：Specimens were collected from clinical patients with infection from January 2006 to December 2008,Acinetobacter baumannii were isolated and the drug sensitivity tested retrospectively.Results：A total of 472 cases of Acinetobacter baumannii were isolated,sputum was the main specimen of which Acinetobacter baumannii were isolated（70.34%）,Acinetobacter baumannii was mainly distributed at ICU（32.84%）.These strains were susceptible to imipenem,meropenem and cefoperazone/sulbactam,the drug resistance rate to other eleven antibiotics was high.Conclusion：Acinetobacter baumannii is susceptible to imipenem,meropenem and cefoperazone/sulbactam and antimicrobial agents should be used rationally to decrease multi-drug resistance.

关 键 词：鲍曼不动杆菌 临床分布 耐药性 头孢哌酮 抗生素 亚胺培南 美洛培南 耐药率 临床标本 舒巴坦 

分 类 号：R446.5[医药卫生—诊断学]