生地注射液对肺间质纤维化患者运动耐量影响的临床研究  

Clinical Study of Shengdi Injection on Exercise Tolerance of Pulmonary Fibrosis Patients

作　　者：闫国良[1] 毕小利[2] 史苗颜[2] 

机构地区：[1]上海中医药大学附属上海市中医医院,上海200071 [2]上海中医药大学附属曙光医院,上海200021

出　　处：《中国中医急症》2010年第3期374-375,493,共3页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的观察和评价生地注射液治疗肺间质纤维化的有效性和安全性。方法肺间质纤维化患者40例随机分为两组,在西医常规治疗基础上,治疗组加用生地注射液,对照组加用生脉注射液。观察两组治疗前后症状改善情况、血气分析、6min步行试验。结果治疗组咯痰、气短症状及症状总积分及PaO2、SaO2的改善均优于对照组;治疗组6min步行距离大于对照组。结论生地注射液能改善肺间质纤维化患者的主要症状,提高血氧分压、血氧饱和度和6min步行距离。Objective： To observe and evaluate the effect and security of Shengdi Injection on pulmonary fibrosis. Methods： 40 patients with pulmonary fibrosis were randomly divided the treatment group and the control group （each 20 patients） . Both groups were treated by conventional therapy. The treatment group was added Shengdi Injection. Before and after treatment, the symptom, the blood air analysis and the 6 minutes walk test were recorded. Results： In the treatment group, the symptom scores of sputum and lack of breath, PaO2 and SaO2 were improved significantly and better than that in the control group. The 6 minutes walk distance of the treatment group was longer than that of the control group. Conclusion： Shengdi Injection could not only improve the symptom of puhnonary fibrosis patients, but also increase the value of PaO2, SaO2 and the 6 minutes walk distance.

关 键 词：生地注射液 肺间质纤维化 血气分析 6min步行试验 

分 类 号：R563.9[医药卫生—呼吸系统]