纳米羟基磷灰石及其复合材料在口腔医学中的应用  

Application of nano-hydroxyapatite and its composite biomaterials in stomatology

作　　者：王云[1] 王青山[1] 

机构地区：[1]滨州医学院,山东省滨州市256603

出　　处：《中国组织工程研究与临床康复》2010年第8期1426-1428,共3页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：山东省自然科学基金项目(Y2008C159)~~

摘　　要：背景:在纳米羟基磷灰石中加入第二相或多相材料合成复合材料已广泛应用于口腔医学中,现已有将纳米羟基磷灰石加入到复合树脂中的报道。目的:综合分析纳米羟基磷灰石及其复合物在口腔领域的广泛应用,展望其应用于口腔材料中的潜在发展。方法:检索Pubmed数据库、EBSCOhost数据库和中国期刊全文数据库相关文献,纳入标准:①具有原创性,论点论据可靠的实验文章。②观点明确,分析全面的文章。③文献主体内容与此课题联系紧密的文章。排除重复的研究和与本综述无关的文献。最后按纳入标准筛选24篇文献进行综述。结果与结论:大量的临床及动物实验表明,纳米羟基磷灰石可以广泛应用于口腔颌面外科、牙体牙髓、口腔种植及口腔其他方面,并随着对其与复合树脂结合的进一步研究,有望在口腔材料中发挥更大的作用。BACKGROUND：The nano-hydroxyapatite（NHA）biomaterials compounded with secondary phase or multiphase materials have been widely used in the domain of stomatology,and there have been several reports regarding the application of compounded NHA with composite resin.OBJECTIVE：To analyze the application progress of NHA in the domain of stomatology,and to prospect the potential significance of NHA in the stomatology materials.METHODS：Databases of Pubmed,EBSCOhost and China Journal Full-text were retrieved to screen out the articles.Inclusion criteria：①The articles possess originality and dependable point and evidence.②The articles have conclusive viewpoint and all round analyses.③The agents of articles contact with this review closely.Exclusion criteria：repetition research and independent literatures with this review.And 24 literatures in accordance with the standard were selected in this study.RESULTS AND CONCLUSION：Many clinical application and animal experiments indicate that NHA has been extensively used in the oral surgery,endodontic,implantation and the other aspects,with the deeply research for combination of NHA and composite resin,NHA hopefully displays greater effectiveness in the stomatology materials.

关 键 词：纳米 羟基磷灰石 复合材料 口腔应用 牙科与颅颌面生物材料 

分 类 号：R318[医药卫生—生物医学工程]