基于同步辐射源的衍射增强成像技术在兔眼球成像中的应用  

Application research of DEI technique based on synchrotron X-ray source in imaging rabbit eyeball in vitro

作　　者：尹红霞[1] 黄志峰[2] 王振常[1] 刘兆会[1] 李勇[1] 朱佩平[3] 

机构地区：[1]首都医科大学附属北京同仁医院医学影像中心,100730 [2]清华大学工程物理系 [3]中国科学院高能物理研究所

出　　处：《中华医学杂志》2010年第11期777-778,共2页National Medical Journal of China

基　　金：国家自然科学基金（30770618）志谢感谢北京同步辐射实验室的黄万霞博士、袁清习博士、王寓越博士在实验中的帮助

摘　　要：目的该实验将探索X射线衍射增强成像（DEI）在兔眼球微细结构成像中的应用。方法在北京同步辐射装置（BSRF）形貌学实验站，应用DEI方法对新西兰大白兔眼球的离体标本进行成像。结果DEI图像清晰显示了眼球的角膜、巩膜、睫状体及睫状肌等结构，显示了DEI技术对眼球的显微成像能力。结论DEI技术具有高对比度、高分辨率和明显的边缘增强等特点，在眼球及其他小器官的微细结构观察方面具有较好的应用前景。Objective To study the application of DEI technique in imaging the small structures of rabbit eyeball. Method DEI technique was used to image the eyeball of New Zealand white rabbit in vitro. The experiments were performed using beamline 4W1A at the topography station of Beijing Synchrotron Radiation Facility （BSRF）. Result DEI image showed clearly the fine structures of the rabbit eyeball, such as the transparent cornea, the sclera, the ciliaris, and the ciliary body. Conclusion DEI is a new X-ray imaging modality which achieves high contrast and spatial resolution. It also showed obvious effect of edge enhancement. DEI has good potential in observing the micro-structures of eyeballs and other small organs.

关 键 词：X线衍射 诊断显像 角膜 

分 类 号：R816.97[医药卫生—放射医学]