不同剂量左布比卡因腰麻在剖宫产术中麻醉并发症评价  

Comparison the complications of anesthesia of the different same dose of levobupivaca for spine anesthesia in patients undergoing caesarean section

作　　者：秦学斌[1] 林高翔[1] 张文斌[1] 赵振海[1] 李敏[1] 

机构地区：[1]广西桂林医学院附院麻醉科,541001

出　　处：《中国实用医药》2010年第9期1-2,共2页China Practical Medicine

基　　金：广西卫生厅基金项目(项目编号:z2006211)

摘　　要：目的研究不同剂量左布比卡因腰麻在剖宫产术中麻醉并发症。方法选择ASAⅠ～Ⅱ级剖宫产妇90例,年龄23～36岁,体质量55～90 kg,身高150～175 cm,随机、双盲分成3组,每组30例,均采用腰硬联合麻醉,L2-3椎间隙穿刺,穿刺成功后蛛网膜下腔分别注入0.75%左布比卡因(加10%葡萄糖至2 ml)A组(7.5 mg)、B组(10 mg)、C组(12.5 mg),注药时间均为1 ml/5 s。给药后用针刺法测定感觉阻滞平面,给药15 min后阻滞平面未达T6水平者经硬膜外分次酌情追加2%利多卡因。麻醉期连续监测BP、HR、ECG和SpO2,观察并记录给药后15 min麻醉平面、麻醉效果、麻醉并发症的发生率及新生儿1 min和5 min的Apgar评分。结果在麻醉效果、麻醉并发症的发生率及新生儿1 min和5min的Apgar评分等方面B、C两组与A组比较无明显差异(P>0.05);在麻醉平面,B、C两组与A组比较有明显差异(P<0.05)。结论不同剂量左布比卡因腰麻在剖宫产术中麻醉并发症无明显差异,10mg和12.5 mg的左布比卡因可取得满意的麻醉平面。Objective Comparison the complications of anesthesia of the different same dose of levobupivaca for spine anesthesia in patients undergoing caesarean section.Methods 90 patients ASA Ⅰ or Ⅱ,23 to 36 years,weighing 55 to 90 kg,highing 150 to 175 cm were randomly divided into three groups（n=30 each）allocated to receiving spinally hyperbaric mixture 2 ml at 1 ml/5 s were combined with 10%glucose and 0.75%levobupivaca（group A 7.5 mg,group B 10 mg,group C 12.5 mg）respectively,and the anesthesia was maintained with epidural administration with 2%li2 docaine if necessary during the operation,after combined spinal epidural anesthesia was applied at the L2-3 interspace.Continuous monitoring BP,HR,ECG and SpO2,anesthesia levels,anesthesia effect,complications of anesthesia,apgar score of the neonateswas.Results Anesthesia effect、complications of anesthesia,Apgar score of the neonateswas were similar in group B and group C than group A（P0.05）.anesthesia levels in group B and group C than group A were significant（P0.05）.Conclusion Levobupivaca are no significant for spine anesthesia in patients undergoing caesarean section,Levobupivaca（10 mg and 12.5 mg）can achieve satisfactory anesthesia levels.

关 键 词：左布比卡因 剂量 腰麻 麻醉并发症 剖宫产术 

分 类 号：R614[医药卫生—麻醉学]