2型糖尿病合并冠心病患者行双源CT冠状动脉造影的对比研究  

Study of dual source CT coronary angiography for detecting coronary stenosis in patients with CHD and type-2 diabetes mellitus

作　　者：刘瑛琪[1] 费军[2] 刘莉[1] 王晓非[1] 高铁山[1] 张朝利[2] 郑冬[2] 陈宁[2] 刘军华[2] 

机构地区：[1]解放军306医院心内科,北京100101 [2]解放军306医院影像科,北京100101

出　　处：《中华老年心脑血管病杂志》2010年第4期299-301,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨双源CT冠状动脉造影在2型糖尿病合并冠心病患者诊断中的应用价值。方法选择临床确诊或疑诊冠心病的2型糖尿病患者88例行CT冠状动脉造影检查,并同期行选择性冠状动脉造影。双源CT的原始数据均行容积再现、曲面重组、最大密度投影及横断面重建。结果 352支血管中(直径≥2 mm),双源CT冠状动脉造影显示≥50%狭窄的血管为163支,占46.3%;选择性冠状动脉造影显示≥50%狭窄的血管为155支,占44.0%。与选择性冠状动脉造影对照分析,双源CT冠状动脉造影评价冠状动脉狭窄(≥50%狭窄)的敏感性、特异性、阳性预测值以及阴性预测值分别为92.3%、89.9%、87.7%和93.7%。结论双源CT冠状动脉造影是检测2型糖尿病患者冠状动脉狭窄的可靠方法。Objective To investigate the value of dual source computed tomography angiography for diagnosis of coronary stenosis in patients with coronary artery disease and type-2 diabetes mellitus. Methods Both dual source computed tomography angiography and coronary angiography were performed in 88 patients who were suspected of having coronary artery disease with type-2 diabetes mellitus. Volume rendering, multiplanar reconstruction, maximum density projection and transverse section reconstruction were performed. Results Of the 352 segments of coronary artery（diameter≥2 mm） of 88 patients,163 were detected to have stenosis ≥50%（46.3%） by dual source spiral computed tomography angiography, 155 were detected to have stenosis ≥50% （44.0 %） by coronary angiography. The sensitivity, specificity, positive predictive value, and negative predictive value of 64 slice spiral computed tomography angiography for detecting stenosis 50%0 was 92.3%0,89.9%0,87.7% and 93.7% respectively. Conclusion This study suggests that dual source 64 slice spiral computed tomography angiography can be used as a reliable diagnostic tool for detecting coronary artery stenosis in patients with type-2 diabetes mellitus.

关 键 词：糖尿病 2型 糖尿病并发症 冠心痛 冠状血管造影术 体层摄影术 X线计算机 

分 类 号：R587.1[医药卫生—内分泌] R541.4[医药卫生—内科学]