利用MC方法计算小鼠体内辐射剂量的体素模型的建立  

A voxel model constructed for calculating mouse internal radiation dose using MC method

作　　者：张晓敏[1] 潘洁[1] 谢向东[1] 杨国山[1] 

机构地区：[1]军事医学科学院放射与辐射医学研究所,北京100850

出　　处：《军事医学科学院院刊》2010年第1期43-45,共3页Bulletin of the Academy of Military Medical Sciences

摘　　要：目的建立一个与蒙特卡罗方法结合进行辐射剂量计算的小鼠体素模型。方法采用一只28g雄性裸鼠的序列切片图像,对此序列图片进行配准、组织识别、分割、颜色赋值后,最后在蒙特卡罗程序MCNP中赋予一定的物理属性。结果建立了一个可以满足剂量分布计算所需精度,并且模拟计算时间适中的小鼠体素模型,此模型器官数量为14个,体素大小为0.2mm×0.2mm×0.2mm。结论该研究所建立的小鼠体素模型可用来进行电离辐射剂量学的模拟计算,以开展放射医学、核医学及空间辐射医学等相关领域的研究。Objective To construct a voxel mouse model combining with Monte Carlo method used for radiation dose calculation.Methods A set of slice images obtained from a nude male mouse （28 g） was utilized,all slice images were registered,some organs or tissues were identified,segmented and filled with specific color,and finally the physical property was defined by MCNP application.Results A mouse model with a voxel size of 0.2 mm×0.2 mm×0.2 mm,consisting of 14 organs or tissues,was constructed,which could satisfy the requirement of precision for radiation dose distribution calculation and moderate computing time.Conclusion The voxel mouse model can be used to calculate the quantity of ionization radiation dosimetry in related areas including radiological medicine,nuclear medicine and space radiation medicine.

关 键 词：小鼠 辐射剂量 体素模型 蒙特卡罗法 MCNP程序 

分 类 号：R144[医药卫生—公共卫生与预防医学]