Vohwinkel残毁性掌跖角皮症  

A case of Vohwinkel keratoderma hereditarium mutilans

作　　者：杨建强[1,2] 王培光[2] 杨森[2] 张学军[2] 

机构地区：[1]湖州师范学院医学院,浙江湖州313000 [2]安徽医科大学皮肤病研究所,安徽医科大学第一附属医院皮肤科,安徽合肥230032

出　　处：《临床皮肤科杂志》2010年第3期167-168,共2页Journal of Clinical Dermatology

摘　　要：报告1例Vohwinkel残毁性掌跖角皮症。患者男,50岁。掌跖增厚脱屑40余年,双手指挛缩10年。体格检查:双掌跖角化增厚,双手除拇指外其余各指可见环形缩窄和挛缩,双足多趾离断。各指(趾)甲板正常。X线检查:双手指骨弯曲变形,部分趾骨破坏消失。诊断为残毁性掌跖角皮症。该例患者不伴有听力异常和鱼鳞病,无阳性家族史。A sporadic case of Vohwinkel keratoderma hereditarium mutilans is reported. A 50-year-old male presented with progressive palmoplantar keratoderma for more than four decades and constricting bands on several fingers and toes for ten years. The clinical features of the patient included thickening of palms and soles, fibrous constricting bands （pseudo-ainhum） on fingers and toes, and several toes were mutilated. X-ray of both hands and feet showed that acral osteolysis, deformity of fingers and mutilation of several toes. The patient had neither ichthyosis nor deafness.

关 键 词：掌跖角皮症 残毁性 

分 类 号：R758.53[医药卫生—皮肤病学与性病学]