初发2型糖尿病强化治疗的血压和血糖及血脂变化  

Changes of blood pressure,blood glucose and blood lipids levels after intensive treatment in incipient diabetes Ⅱ patients

作　　者：赵晓红[1] 徐哲荣[1] 吕雪英[1] 张勤[1] 杨云梅[1] 

机构地区：[1]浙江大学医学院附属第一医院干部病房,浙江杭州310003

出　　处：《浙江大学学报（医学版）》2010年第2期198-201,共4页Journal of Zhejiang University(Medical Sciences)

基　　金：国家"十一五"科技支撑计划研究项目(2006BAI02B08)

摘　　要：目的:比较初发2型糖尿病强化治疗与常规治疗的血糖和血脂及血压控制情况。方法:160例初发糖尿病患者按照入组时间顺序分成2组(先收集常规治疗组80例,再收集强化治疗组80例),治疗前检测空腹血糖(FBG)、糖化血红蛋白(HbA1C)、血压、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-C(LDL-C)和谷丙转氨酶(ALT)及谷草转氨酶(AST)。常规治疗组予门诊常规治疗,强化治疗组定期检测血压和血糖及血脂,对未达标患者调整治疗方案,直至血压和血糖及血脂达到治疗标准。6个月后再次检测相关指标,比较2组各观察指标的差异。结果:6个月时强化治疗组TC和LDL-C,与常规治疗组比较均有明显降低(P<0.05)。结论:2型糖尿病强化干预治疗在控制血糖的同时能使血脂得到进一步控制。Objective： To evaluate the effect of intensive treatment on the blood sugar,blood lipids and blood pressure levels in incipient diabetes Ⅱ patients.Methods： One hundred and sixty incipient diabetes patients were allocated into two groups according to chronological order：80 cases received routine treatment and 80 cases received intensive treatment.Fasting blood-glucose（FBG）,glycosylated hemoglobin（HbA1C）,blood pressure,blood cholesterol（TC）,triglyceride（TG）,LDL cholesterol-C（LDL-C）,alanine aminotransferase（ALT） and aspertate aminotransferase（AST） were tested before treatment.For intensive treatment group blood pressure,blood sugar and blood lipids were regularly tested,and the therapeutic protocols were adjusted according to the test results until the therapeutic target reached.After six months,HbA1C,blood pressure,TC,LDL-C,ALT and AST were tested again and comparison was made between the two groups.Results： There was a significant decrease in TC and LDL-C in the intensive treatment group compared with those in the routine treatment group（P0.05）.Conclusion： The intensive treatment on the incipient diabetes Ⅱ patients facilitate the control of the blood lipids and blood sugar.

关 键 词：糖尿病 2型/药物疗法 血压/分析 血糖/分析 脂类/血液 干预性研究 2型糖尿病 强化治疗 

分 类 号：R587.1[医药卫生—内分泌]