不同能量密度激光照射家兔耳静脉后的温度变化  

Microscopic measurement of rabbit ear veins and changes of skin temperature after laser pulsed irradiation

作　　者：周国瑜[1,2] 赵婷婷[1,2] 李平平[1,2] 沈玲悦 徐青[1,2] 

机构地区：[1]上海交通大学医学院附属第九人民医院.口腔医学院口腔颌面外科 [2]上海市口腔医学重点实验室,上海200011

出　　处：《中国口腔颌面外科杂志》2010年第2期178-182,共5页China Journal of Oral and Maxillofacial Surgery

基　　金：上海市科学技术委员会资助项目(08DZ2271100);上海市重点学科建设项目(S30206)~~

摘　　要：目的:观察不同波长激光和不同激光能量密度照射家兔耳静脉后的温度改变。方法:采用立体数码体视显微镜,定量测量10只家兔(0只耳朵、80个区域)的静脉主干和I级分支的平均管径大小。采用PDL585nm脉冲染料激光和长脉宽1064nm Nd:YAG激光,分别对5只家兔(10只耳朵、40个区域)的静脉进行激光照射。PDL585nm激光能量密度分别为6、7、8、9、10J/cm2,1064nm Nd:YAG激光能量密度分别为14、160、180、200、220J/cm2。利用数码热敏温度仪测量激光照射后的兔耳皮肤温度改变。结果:家兔耳静脉的主干静脉管径为(1.0120±0.1900)mm,I级分支静脉管径为(0.4523±0.1074)mm。PDL585nm激光照射后,兔耳皮肤温度即刻升高至39.9℃～46.0℃;1064nm Nd:YAG激光照射后,兔耳皮肤温度即刻升高至38.6℃～45.4℃。结论:脉冲染料激光PDL585nm、1064nmNd:YAG激光照射均致兔耳皮肤温度升高,并与能量密度呈正比。PURPOSE：To investigate the skin temperature changes of rabbit ears after pulsed laser treatments.METHODS：Ten healthy New Zealand rabbit with 20 ear vein models was used for the study.The diameter of the rabbit ear veins was measured by a three-dimensional microscope.After different energy density of 6J/cm^2,7J/cm^2,8J/cm2,9J/ cm^2,10J/cm^2 PDL585nm and 140 J/cm^2,160 J/cm^2,180 J/cm^2,200 J/cm62,220 J/cm^2 1064nm Nd：YAG laser irradiation on those veins,the contemporary skin temperature changes of rabbit ear veins was measured and analyzed.RESULTS：The average diameter of portal vein of rabbit ears was（1.0120±0.1900）mm,the average diameter of branch I veins of rabbit ear was（0.4523±0.1074）mm.The immediate temperature increase of rabbit ear skin after PDL 585nm irradiation ranged from 39.9℃ to 46.0℃.The immediate temperature increase of rabbit ear skin after 1064nm Nd：YAG laser irradiation ranged from 38.6℃ to 45.4℃.CONCLUSION：PDL585nm and 1064nm Nd：YAG laser irradiation can increase the skin temperature of rabbit ear which is proportional to the dose of laser irradiation.DCD can decrease the extent and shorter the time of purpura lasting,decrease heat damage of the skin and thus improve the clinical effect.

关 键 词：家兔 耳静脉 脉冲染料激光 长脉冲1064nm激光 血管测量 激光 剂量 效应 

分 类 号：R454[医药卫生—治疗学]