金银花液热湿敷防治放疗加西妥昔单抗致皮肤反应的效果观察  

The efficacy of wet compress with flos lonicerae for cetuximab correlative erythra

作　　者：张海霖[1] 王国蓉[1] 张仕碧[1] 肖红英[1] 钟玉仙[1] 朗锦义[1] 

机构地区：[1]成都市四川省肿瘤医院放疗科,610041

出　　处：《中华护理杂志》2010年第4期307-310,共4页Chinese Journal of Nursing

摘　　要：目的探讨金银花液热湿敷对同步放化疗联合西妥昔单抗所致特有皮肤反应的临床护理效果。方法将42例同步放化疗联合西妥昔单抗患者按随机单盲分为观察组23例,用5g/100ml浓度的金银花水煎液,按皮疹反应给予每日2-5次热湿敷,1级每日2次,2级每日3次,3级每日5次。1周为一疗程,同时给予皮肤保护性护理;对照组19例给予温水湿敷,其余护理方法同观察组。观察干预后3d、7d两组皮疹的变化情况。结果两组患者皮疹消退比较有统计学意义(P<0.05),观察组皮疹消退明显优于对照组。结论金银花液热湿敷处理同步放化疗联合西妥昔单抗所致特有皮疹疗效确切,安全经济,值得推广。Objective To evaluate the efficacy of wet compress with herbs for cetuximab correlative erythra. Methods Fortytwo patients received radiochemotherapy combined with cetuximab were randomly divided into two groups. The 23 patients in the experimental group received one-week wet compress with 5g/100ml flos lonicerae twice to five times per day. While the 19 patients in the control group were given wet compress with tepid water. The efficacy on day 3 and day 7 were observed. Results The efficacy on erythra was better in the experimental group than that of control group （P〈0.05）. Conclusion The wet compress with flos lonicerae is effective,safe and economical for the treatment of cetuximab correlative erythra,which is deserved to be applied in clinical practice.

关 键 词：西妥昔单抗 金银花 热敷 皮疹 

分 类 号：R473.73[医药卫生—护理学]