中药浸膏粉吸湿过程模型及应用研究  

Study on moisture sorption process model and application traditional Chinese medicine extract powder

作　　者：林婷婷[1] 何雁[1] 肖雄[1] 袁亮[1] 饶小勇[1] 罗晓健[1] 

机构地区：[1]江西中医学院中药固体制剂制造技术国家工程研究中心,江西南昌330006

出　　处：《中国中药杂志》2010年第7期847-851,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30860382)

摘　　要：目的:研究中药浸膏粉的吸湿过程特点,建立数学模型,为深入研究中药浸膏吸湿行为提供一种新的方法,为确定生产周期、预测产品稳定性提供参考。方法:分析中药浸膏粉吸湿过程,应用物质质量守恒定律、费克扩散第一定律,建立双指数吸湿过程模型,对中药浸膏吸湿数据进行拟合,并与其他常用5种模型比较,评价双指数模型的效果。结果:经统计分析可知,双指数模型、Weibull分布模型、一级过程模型的决定系数(R2)均较大,残差平方和(RSS),AIC值均较小,综合3种模型的实际应用意义,认为双指数模型更适用于模拟中药浸膏粉的吸湿过程。结论:所建立的双指数模型适合表征中药浸膏粉的吸湿过程。Objective： Study on the characteristics of Traditional Chinese medicine extract powder Moisture Sorption Process, to establish a mathematical model, provide a new method for in-depth study of Traditional Chinese medicine extract powder moisture sorption behavior, and provide a reference for determine the production cycle and predict product stability. Method： Analysis of Traditional Chinese medicine extract powder moisture absorption process, utilize the law of conservation of mass and Fick’s first law to establish the double exponential absorption model, fitting the moisture absorption data and compare with other commonly used five kinds of model, to estimate the double-exponential absorption model. Result： The statistical analysis shows that the R2 value of double exponential model is the largest, while the RSS, SEE, RMS values are smallest, which indicating the double exponential model is more suitable for simulating the process of Traditional Chinese medicine extract powder moisture absorption. Conclusion： Double exponential model fitting is superior to another five kinds of models, indicating the double exponential is suit for superficial syndrome the process of traditional Chinese medicine extract moisture absorption.

关 键 词：中药浸膏粉 吸湿过程 数学模型 

分 类 号：R283[医药卫生—中药学]