马尔可夫药物动力学模型B  

The Markov Model B in Pharmacokinetics

作　　者：杨静化[1] 张琪[1] 

机构地区：[1]中国药科大学数学室,南京210009

出　　处：《生物数学学报》1998年第2期132-135,共4页Journal of Biomathematics

摘　　要：本文建立的Markov模型B适于计算肾、心、脑、皮肤、脂肪、肌肉中的血药浓度,它具有生理药动学模型的优点，即动力学参数具有解剖学和生理学意义，又能象房室模型一样用简单、优美的形式表示模型的解.The Markov model B developed in this paper is applicable for the calculation of the blood concentration in the organs such as kidney,brain,skin,fat and muscle.It has the advantage of physiological pharmacokinetics model:its kinetic parameters have anatomy and physiological meanings,and its solution can be expressed succinctly like the atrium model.

关 键 词：马尔可夫过程 马尔可夫模型 药物动力学模型 

分 类 号：R912[医药卫生—药学]