南极环境对考察队员儿茶酚胺含量的影响  

CHANGES OF URINE AND PLASMA CATECHOLAMINE OF EXPEDITION MEMBERS IN ANTARCTIC ENVIRONMENT

作　　者：朱广瑾[1,2] 段岩平[1,2] 周朝凤[3] 张莹[4,5] 薛全福[4,5] 

机构地区：[1]中国医学科学院基础医学研究所 [2]协和医科大学基础医学院 [3]北京医科大学精神卫生研究所 [4]中国医学科学院基础医学研究所协和医科大学基础医学院 [5]北京大学心理学系

出　　处：《极地研究》1998年第4期305-309,共5页Chinese Journal of Polar Research

基　　金：八.五国家科技攻关南极项目;自然科学基金

摘　　要：报道了中国第八次南极考察队（长城站）队员赴南极前、居留南极及回国后尿、血浆的去甲肾上腺素（ＮＥ）和肾上腺素（Ｅ）含量变化，以探讨考察队员在居留南极期间普遍存在生理和心理变化的物质基础。结果表明：考察队员到达长城站２周时尿中ＮＥ急剧增高（与赴南极前相比Ｐ＜０．０５），越冬后（居留南极１年２周）ＮＥ大幅度下降（与到达２周时相比Ｐ＜０．００１），考察结束回国后ＮＥ恢复到赴南极前水平。尿中Ｅ含量在到达南极２周时同样显著升高，且增高幅度大于ＮＥ（与赴南极前比较Ｐ＜０．００１），越冬后Ｅ水平比到达２周时有所降低（Ｐ＜０．０５），回国后Ｅ水平没有恢复。提示，儿茶酚胺变化参与综合应激反应过程，Ｅ受心理影响大于生理因素。还发现部分考察队员惧怕抽血，故测定尿儿茶酚胺含量更切实可行。经酸化处理的尿样品在短期内温度（室温）对儿茶酚胺含量影响不大，因此，从南极实地取样返回国内检测及进行南极医学方面的研究完全可行。The changes of urine and plasma catecholamines, norepinephrine(NE) and epinephrine(E), were investigated in 16 Antarctic expedition members(Great Wall Station) under extreme environmental condition by Spectrophotofluorescent and radioenzymatic assay. Samples were taken at different time:(1)before leaving to Antarctica;(2)2 weeks after arrival at Antarctica;(3)1 year and 2 weeks after arrival and (4) after returning back to China.Results showed that a rapid increase of urinary NE in Antarctica (2) decreased significantly at(3),and returned to normal content at(4).The increase of urinary E was greater than that of NE at Antarctica (2),but kept high level at (4). The results indicated that activation of sympathetic system was involved in syndromic stress, especially psychological responses was associated with high E level. In addition, catecholamines were not affected by temperature and determinative time in room temperature during 3 monthes.

关 键 词：南极 考察队员 儿茶酚胺 环境 尿 

分 类 号：R446.122[医药卫生—诊断学]