阿莫西林与维多利亚蓝B的显色反应及应用  

Study on the color reaction of amoxicillin with victoria blue B and its applications

作　　者：江虹[1] 张华[1] 谢虹[1] 

机构地区：[1]长江师范学院化学化工学院,重庆408100

出　　处：《化学研究与应用》2010年第4期483-486,共4页Chemical Research and Application

基　　金：重庆市教委科技基金项目(KJ071304)资助;长江师范学院科研项目(2008xky39)资助

摘　　要：The color reaction of amoxicillin with victoria blue B was studied.A novel visible spectrophotometric method for the determination of amoxicillin has been established.Under pH 8.50～10.5 condition,victoria blue B reacteds with amoxicillin to form red ion association complex.The maximum absorption wavelength was at 630nm and the apparent molar absorptivity(ε) was 2.67×104 L·mol-1·cm-1 and the linear ranges was 0～5.5 mg·L-1.Amoxicillin obey Beer’s law in definite concentration range.The optimum reaction conditions and the methodological precision were studied simultaneity.The method was simple and rapid and sensitive for the determination of amoxicillin.This method has been applied to the determination of amoxicillin is in the city sell amoxicillin medicament is in point and average recovery at 98.2%～101.0%.The color reaction of amoxicillin with victoria blue B was studied. A novel visible spectrophotometric method for the determination of amoxicillin has been esrablished. Under pH 8.50 - 10. 5 eondition,victoria blue B reaeteds with amoxieillin to form red ion association complex. The maximum absorption wavelength was at 630nm and the apparent molar absorptivity（ε） was 2. 67 ×10^4 L · mol^-1 ·cm^-1 and the linear ranges was 0 - 5. 5 mg · L^-1. Amoxicillin obey Beer＇ s law in definite concentration range. The optimum reaction conditions and the methodological precision were studied simultaneity. The method was simple and rapid and sensitive for the determination of amoxicillin. Tbis method has been applied to the determination of amoxicitlin is in the city sell amoxieillin medicament is in point and average recovery at 98. 2% - 101.0%.

关 键 词：阿莫西林 维多利亚蓝B 显色反应 分光光度法 

分 类 号：O657.3[理学—分析化学]