异帕米星治疗呼吸系统感染患者的临床疗效与安全性评价  

Evaluation of clinical efficacy and safety of isepamicin

作　　者：贾兴泽 吴天荣[1] 张大会[1] 

机构地区：[1]米易县人民医院内科,四川米易617200

出　　处：《西部医学》2010年第4期654-655,共2页Medical Journal of West China

摘　　要：目的观察并帕米星治疗呼吸系统感染患者的临床疗效及安全性。方法选取呼吸系统感染患者110例，随机分为治疗组和对照组各55例；对照组治疗：在0．9％生理盐水250ml中加入头孢塞肟钠3．0g，静脉滴注，每日两次；治疗组在对照组用药的基础上加入异帕米星，400mg静脉滴注，每日两次；两组疗程均为7～10天，疗程结束后，评价两组的疗效及不良反应。结果治疗组临床疗效和对细菌的消除率均优于对照组（P〈0．05），不良反应发生率两组间差异不显著（P〉0．05）。结论异帕米星临床对呼吸系统感染患者的治疗，疗效可靠，安全性高，具有临床应用价值。Objective To observe clinical efficacy and safety of iseparaicin. Methods 110 patients with respiratory infections were randomly divided into treatment group （55 cases） and control group （55 cases）. Treatment group was treated with isepamicin and cefotaxime sodium. Control group was treated with cefotaxime. Results Clinical efficacy of the treatment group was better than that of the control group. The incidence of adverse reactions was no significant differences. Conclusion Clinical efficacy of isepamicin is reliable and safe.

关 键 词：异帕米星 临床疗效 安全性 

分 类 号：R969.4[医药卫生—药理学]