克拉玛依市区胆石症患者胆汁菌群分布及药物敏感分析  

Cultivation and drug sensitive test of bile bacteria in patients with Cholelithiasis in Kelamayi city

作　　者：罗超英[1] 刁红亮[1] 乌尔班提.木尔沙里木 卢宝卫[2] 王金龙[1] 邢育霞[1] 夫尔多斯[1] 

机构地区：[1]新疆克拉玛依市中心医院普外科,新疆克拉玛依834000 [2]新疆克拉玛依市中心医院细菌室,新疆克拉玛依834000

出　　处：《新疆医科大学学报》2010年第2期183-185,共3页Journal of Xinjiang Medical University

摘　　要：目的观察并分析胆石症患者胆汁中菌群分布及胆汁培养细菌药物敏感谱,以指导临床选择抗生素。方法选择胆石症患者450例,通过术中采集胆囊及胆总管的胆汁进行细菌培养及药敏感验。结果胆汁细菌培养阳性率为26.2%(118/450),其中革兰阴性菌占66.9%(83/124),革兰阳性细菌占29.8%(37/124),前三位分别是大肠埃希氏菌、肺炎克雷伯菌、粪肠球菌,并且有4例真菌感染。结论胆汁中病菌种类较多,主要为革兰阴性杆菌,但革兰阳性球菌呈上升趋势,药物敏感谱亦有明显变化,临床常用抗生素耐药性明显增加,应根据药敏合理选择抗生素。Objective To observe the bacteria distribution of bile and it＇s drugs sensitivity in patients with Cholelithiasis,to guide the selection of reasonable antibiotics.Methods Bile of 450 cases of patients with cholelithiasis were collected and cultured respectively and tested for antibiotics susceptibility.Results Bacteria positive rate of these 450 bile samples was 26.2%（118/450）,including Gram-negative bacteria 66.9%（83/124）,Gram-positive bacteria 29.8%（37/124）,and 4 fungal strains.Conclusion The pathogenic microorganisms in bile are very various,Gram-negative strain is still most common,but the rate of Gram-positive strains is rising,and drug sensitivities of the bacteria in biles were changed significantly in recent years.It suggested that the cultured results of bile samples should be emphasized,and should use the antibiotics properly.

关 键 词：胆石症 胆汁培养 细菌耐药 细菌 

分 类 号：R657.4[医药卫生—外科学] R446[医药卫生—临床医学]