化痰祛瘀方对痰浊血瘀型不稳定型心绞痛介入术后sCD40L及hs-CRP的影响  

Influence of Huatanquyu-Decoction in the Expression level of serum sCD40L and hs-CRP in the treatment of unstable angina pectoris after percutaneous coronary intervention

作　　者：刘宁[1] 姚福梅[1] 王霞[1] 彭威[1] 

机构地区：[1]大连市第二人民医院,辽宁大连116011

出　　处：《中国医药导报》2010年第10期142-143,共2页China Medical Herald

摘　　要：目的:探讨化痰祛瘀方对痰浊血瘀型不稳定型心绞痛介入术后患者sCD40L及hs-CRP的影响。方法:将78例接受冠脉动脉介入治疗的UA患者,随机分为对照组(39例)与治疗组(39例)。前者予常规西药治疗,后者于常规西药治疗基础上加用化痰祛瘀方,均治疗3周。比较两组患者间术前、术后sCD40L及hs-CRP的水平。结果:两组患者术后第1天与术前比较sCD40L和hs-CRP的水平有显著性差异(P<0.01),术后3周末对照组sCD40L及hs-CRP的水平显著高于治疗组,(P<0.05)。结论:化痰祛瘀方可显著降低痰浊血瘀型不稳定型心绞痛冠脉介入术后sCD40L及hs-CRP的水平。Objective：To explore the effect of Huatanquyu-Decoction in the expession level of serum soluble CD40L and hs-CRP in the treatment of unstable angina pectoris after percutaneous coronary intervention. Methods：78 patients with UA were randomly divided into two groups. Before and after PCI treatment,39 cases were in control group taking routine therapy and 39 cases were in treament group taking Huatanquyu-Decoction in the first day,besides basic treatment. Serum soluble CD40L and hs-CRP were measured in 2 groups treatment before PCI and the 1st,3 weeks after PCI. Results：There was no significant difference in serum soluble CD40L and hs-CRP between the two groups before treatment （P〉0.05）. On the 1st day after PC1,the level of serum soluble CD40L and hs-CRP were all slightly increased in both groups,On the 21th day after PCI,there was a little decrease of Serum soluble CD40L and hs-CRP in the control group,while it was significantly decreased in the treatment group （P〈0.05）. Conclusion：A changeable regularity of serum soluble CD40L and hs-CRP can be found within the patients of UA before and after PCI. Huatanquyu Decoction has effects of anti-inflammation.

关 键 词：化痰祛瘀方 不稳定型心绞痛 冠状动脉介入治疗 SCD40L HS-CRP 

分 类 号：R541.4[医药卫生—心血管疾病]