淋必治的极谱研究  

Study on the Polarography of Spectinomycin

作　　者：谭学才[1] 吴少尉[1] 

机构地区：[1]湖北民族学院化工系

出　　处：《分析试验室》1998年第6期24-27,共4页Chinese Journal of Analysis Laboratory

基　　金：湖北省教委资助

摘　　要：在０．１ｍｏｌ／ＬＨＡｃ－ＮａＡｃ（ｐＨ４．５０）支持电解质中，淋必治（ＳＰＥ）有一灵敏的示波极谱导数还原峰，峰电位ＥＰ＝－０．９８Ｖ（ｖｓ．ＳＣＥ）。峰电流与ＳＰＥ的浓度在２．０×１０－７～８．０×１０－５ｍｏｌ／Ｌ范围内呈线性关系，最低检出限为５．０×１０－８ｍｏｌ／Ｌ。该法用于注射针剂中ＳＰＥ含量的测定，结果良好。文中对ＳＰＥ的极谱行为、电极过程及反应机理进行了探讨。In 0.1mol/L HAc NaAc(pH=4.50) supporting electrolyte, a reduction peak of SPE is obtained by single sweep polarography.The peak potential is E p=-0.98V( vs .SCE).The peak current changes linearly with the concentration of SPE in the range of 2.0×10 -7 ～8.0×10 -5 mol/L with a detection limit of 5.0×10 -8 mol/L.This method has been used to determine the content of SPE in injections.The polarographic behavior,electrode process and reaction mechanism have been studied in detail.

关 键 词：淋必治 极谱分析 电化学行为 测定 

分 类 号：R978.1[医药卫生—药品]