芳基异方酰胺与HMPA及一些羧酰胺的反应  

Reaction of Iso - Squarylram Amide with HMPA and Some Carboxylic Amides

作　　者：陈益钊[1] 李聚才[1] 黄锋[2] 陈凌勇[3] 

机构地区：[1]四川大学化学系,成都610064 [2]中国人民解放军防化研究院,北京102205 [3]泸州医学院,泸州646000

出　　处：《有机化学》1998年第6期562-566,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金

摘　　要：研究了1,3-双芳基异方酰胺与六甲基磷酰三胺(HMPA)及其它羧酰胺的反应制得了15个既含芳胺基又含脂肪基的不对称方酰胺。该反应提供了制备既含芳胺基又含二甲胺基、甲胺基和乙胺基的不对称方酰胺的较为有效的方法。对反应机理作了初步讨论。In the chemistry of squaric acid, we find first that 1,3- diaryl iso - squarylium amide can react with HMPA and other carboxylic amides. Fifteen asymmetric amides of squaric acid containing aryl and alkyl are synthesized. This novel reaction can be used for effective preparation of asymmetric amide of squaric acid containing aryl and dimethylamino, methylamino, ethylamino. The possible mechanism of reaction is discucssed preliminarily.

关 键 词：异方酰胺 酰胺 环丁烯二酮 方酸化学 方酰胺 

分 类 号：O624.5[理学—有机化学]