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出 处:《中国医药指南》2010年第12期12-14,共3页Guide of China Medicine
摘 要:目的探讨糖尿病合并败血症菌种分布特点和耐药谱的变化,指导临床用药。方法回顾性分析了2007年5月至2009年5月所有血培养阳性且经临床资料证实的39例糖尿病合并败血症患者。结果共获阳性血培养株40份。居前3位的是大肠埃希菌、克雷伯菌菌、金黄色葡萄球菌;革兰阴性菌出现多重耐药且耐药水平增高。结论革兰阴性菌仍占主流,细菌耐药形势严峻,应重视细菌耐药性的动态监测,常规开展产酶菌检测,指导抗生素的合理应用,延缓预防耐药菌株的扩散流行。Objective To investigate the trend of the diabetic septicemias inside hospital, and the distribution and drug resistance of the causing bacteria. Method A retrospective analysis was made for 39 cases of septicemias diagnosed by blood cultures and clinical data, which were from may 2007 to may 2009. Results 40 strains of microorganisms were isolated from blood cultures. Among them the first three pathogens were Escherichia coli, Enterobacter cloacace, Staphylococcus aureus. 5 strains were fungus septicemia with hospital acquired. The higher rate and multiple drug resistance was seen in Gram- negative coccus. Conclusions Gram-negative coccus still were major one, and fungus septicemias demonstrated an increasing occurrence trend. The situation of antibiotic resistance was very serious now, so it is important to monitor the bacteria resistance to antibiotics and to detect the strains which can produce enzymes regularly for directing the clinical doctor to use antibiotics reasonably, so as to relieve and prevent the spread of drug resistance strains.
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