南昌地区7251例门诊皮肤黏膜真菌病及病原菌分析  

Clinical phenotype and pathogen profile of 7251 cases of cutaneous and mucous mycosis in Nanchang region

作　　者：占萍 李智华 江情 金云 陶丽 罗云鹏 耿承芳 

机构地区：[1]江西省皮肤病专科医院,南昌330001

出　　处：《中华皮肤科杂志》2010年第3期156-159,共4页Chinese Journal of Dermatology

摘　　要：目的了解南昌地区皮肤科门诊真菌感染性疾病的构成情况。方法统计我院门诊2006～2008年期间诊断的所有皮肤和黏膜真菌病，分析病种和致病菌种与年龄、性别和发病季节的关系。结果皮肤和黏膜真菌病共7251例，男女比为2．3：1。股癣2702例占37．3％、花斑糠疹1505例占20．8％，手癣727例占10．0％，分别居第1～3位。除花斑糠疹未进行培养外，培养阳性菌株4953株，优势菌为红色毛癣菌（69．9％）、念珠菌（20．4％）和紫色毛癣菌（4．5％）。不同年龄段、性别及季节的病种和病原菌分布差异具有统计学意义。结论南昌地区皮肤门诊中皮肤和黏膜真菌病以股癣病例数最多，致病菌主要为红色毛癣菌，头癣致病菌主要为紫色毛癣菌，与其他地区报道不尽相同。Objective To profile the phenotype and pathogens of cutaneous and mucous mycoses in a dermatology outpatient clinic in Nanchang region. Methods A review was performed to assess cutaneous and mucous mycoses diagnosed in the dermatology outpatient clinic of Dermatology Hospital of Jiangxi Province from 2006 to 2008. The relationship of clinical phenotype and pathogens to season, patients＇ age and gender was analyzed. Results A total of 7251 cases were collected, and the ratio of male to female patients was 2.3 ： 1. The most prevalent mycoses included tinea cruris （2702, 37.1%）, pityriasis versieolor （1505, 20.8%） and tinea manus （727, 10.0%）. In total, 4953 fungal strains were isolated from all the patients except for those with pityriasis versicolor; of them, Trichophyton rubrum accounted to 69.9%, Candida to 20.4%, and Trichophyton violaceum to 4.5%. Season, patients＇ age and gender were found to be associated with clinical phenotypes and pathogens of mycoses. Conclusions In the dermatology outpatient clinic of Nanchang region, tinea cruris is the most common superficial fungal disease, with the predominant pathogen being Trichophyton rubrurn. Trichophyton violaceum is the primary pathogen of tinea capitis, which is different from other reports.

关 键 词：皮肤真菌病 有丝分裂孢子真菌 

分 类 号：R756[医药卫生—皮肤病学与性病学]