超声造影定量分析体外冲击波碎石后肾皮质血流灌注  

Quantitative evaluation of kidney cortex hemoperfusion with contrastenhanced ultrasound after extracorporeal shock wave lithotripsy

作　　者：王丹郁[1] 梁峭嵘[1] 谭清波[1] 俞抒姝[1] 黄春燕[1] 刘照宏[1] 梁彤[1] 

机构地区：[1]广州中医药大学附属佛山市中医院超声科,广东佛山528000

出　　处：《中国介入影像与治疗学》2010年第2期150-152,共3页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的探讨超声造影(CEUS)结合时间-强度曲线分析体外冲击波碎石术(ESWL)前后肾皮质血流灌注的改变及其临床意义。方法对30例诊断为肾结石患者行ESWL,于ESWL前、ESWL后即时分别行CEUS检查。用ACQ软件定量测量碎石靶区肾皮质血流灌注参数值,观察指标为造影剂到达时间(AT)、达峰时间(TTP)、达峰强度(PI)及速度参数(β)。结果AT、TTP、β值ESWL前后差异无统计学意义(P>0.05),PI值ESWL前后差异有统计学意义(P<0.05),ESWL后PI值小于ESWL前PI值。结论CEUS定量分析技术能显示ESWL前后肾皮质血流灌注的变化,反映肾的微小损伤,可以成为监测ESWL肾损伤的新手段。Objective To investigate the changes of kidney cortex hemoperfusion before and after extracorporeal shock wave lithotripsy（ESWL） with contrast-enhanced ultrasonography（CEUS） and time-intensity curve.Methods Thirty patients of renal calculi were treated with ESWL and examined with CEUS before and after ESWL.Renal cortex blood perfusion parameters of the lithotriptic areas,including the contrast agent arrival time（AT）,time to peak（TTP）,peak intensity（PI） and velocity parameters（β） were quantitatively measured with ACQ software.Results The value of AT,TTP and β were not significantly different before and after ESWL（P0.05）.PI value after ESWL was lower than that before ESWL（P0.05）.Conclusion CEUS can quantitatively evaluate the changes of kidney cortex hemoperfusion after ESWL,and reflect the minor renal damage resulted from ESWL.CEUS can be used as a new method of observing and evaluating the renal damage caused by ESWL.

关 键 词：超声检查 体外冲击波碎石 肾皮质 造影剂 血流动力学 

分 类 号：R692.4[医药卫生—泌尿科学] R445.1[医药卫生—外科学]