WHBE兔的血液学指标测定与比较  

Determination and Comparison of Hematological Indices in WHBE Rabbits

作　　者：应华忠[1] 寿旗扬[1] 陈民利[1] 潘永明[1] 王辉[1] 林琳[1] 朱科燕[1] 王德军[1] 徐孝平[1] 

机构地区：[1]浙江中医药大学动物实验研究中心／比较医学研究中心,杭州310053

出　　处：《实验动物与比较医学》2010年第1期44-47,共4页Laboratory Animal and Comparative Medicine

基　　金：浙江省公共科技基础平台项目（Dwpt-bz-12,2007F8003）;2.浙江省卫生高层次创新人才.±立养工程项目.

摘　　要：目的测定和比较分析WHBE兔、日本大耳白兔、新西兰白兔的血液学指标，揭示WHBE兔的血液学特性。方法选择WHBE兔、日本大耳白兔、新西兰白兔各40只，雌雄各半，耳动脉采血，应用BayerADVIA120五分类血球分析仪测定红细胞、白细胞、血小板等血液细胞参数。结果①性别因素对WHBE兔的％NEUT、％LYMP、MCH、MCHC、RDW等有显著差异（P〈0．05，P〈0．01），其它指标雌雄性别间均无显著差异（P〉0．05）：②WHBE兔的白细胞参数和红细胞参数与日本大耳白兔和新西兰白兔存在着显著差异，如白细胞数目明显低于日本大耳白兔（P〈0．01），淋巴细胞和血红蛋白含量均明显高于日本大耳白兔和新西兰白兔（P〈0．01）。结论WHBE兔有其自身的特性，也有其兔种群的共性，WHBE兔的血液学生理指标与人类较为接近。Objective To determine and comparative analysis of hematological parameters in WHBE rabbits, Japanese White rabbits and New Zealand White rabbits, and further reveal on hematological characteristics of WHBE rabbits. Methods Fourty in each of WHBE rabbits, Japanese White rabbits and New Zealand White rabbits, half male and female, the anticoagulant blood was sampled from the central artery of ear, and then hematological parameters indexes were determined by Bayer ADVIA 120 automatic blood analyzer. Results （1） Gender factor has significant influences on neutrophil, lymphocyte, MCH, MCHC and RDW in WHBE rabbits （P〈0.05, P〈0.01）; （2） Leukocytes amounts was lower in WHBE rabbits than that of Japanese White rabbits （P〈0.01）, lymphocyte and hemoglobin were higher in WHBE rabbits than those of Japanese White rabbits and New Zealand White rabbits （P〈0.01）. Conclusion WHBE rabbit has its own special characteristics, also has its population characteristics in common, and the hematological parameters in WHBE rabbits were similar to those of human being.

关 键 词：WHBE兔 日本大耳白兔 新西兰白兔 血液学 

分 类 号：Q95-33[生物学—动物学]