加用地塞米松和干扰素治疗婴儿肝炎综合征30例疗效观察  

作　　者：黄晓夏[1] 

机构地区：[1]广东省汕头市妇幼保健院儿科,505041

出　　处：《浙江临床医学》2010年第4期355-356,共2页Zhejiang Clinical Medical Journal

摘　　要：目的评价地塞米松与干扰素治疗婴儿肝炎综合征的疗效。方法治疗组30例，在常规治疗的基础上，加用地塞米松与干扰素治疗；对照组30例，只予常规治疗。对两组患者并进行疗效比较，包括血清总胆红素和ALT、AST下降情况。结果治疗组血清总胆红素、ALT、AST明显降低，疗效显著，治疗时间缩短，两组比较差异有统计学意义（χ2=4．68，P〈0．05）。结论加用地塞米松与干扰素治疗婴儿肝炎综合征，能缩短疗程，提高疗效。Objective To evaluate the therapeutic effect of combining dexamethasone and interferon in treating the baby hepatitis syndrome. Method Patients were divided into two groups, treating group and control group, in the treating group, dexamethasone and interferon were added to the 30 patients in addition to the conventional treatment; in the control group, 30 patients were given the conventional treatment only, the therapeutic effects were compared （including the decrease of serum total bilirubin, ALT, AST）. Result In the treating group, serum total bilirubin, ALT, AST decreased significantly, the therapeutic effect was significant, the course of treatment shortened significantly also （χ2 = 4. 68, P 〈 0. 05 ）. Conclusion Adding dexamethasone and interferon in the treatment of baby hepatitis syndrome can shorten the course of treatment, and improve the therapeutic effect.

关 键 词：地塞米松 干扰素 婴儿肝炎综合征 疗效 

分 类 号：R725.126[医药卫生—儿科]