莫西沙星联合阿奇霉素治疗支原体肺炎的研究  

Study on the Effect of Moxifloxacin Combined with Azithromycin in Treating Mycoplasma Pneumonia

作　　者：陈经云[1] 崔春宁[1] 蔡孝桢[1] 方浩威[1] 

机构地区：[1]广东省东莞市厚街医院,广东东莞523945

出　　处：《河北医学》2010年第3期272-274,共3页Hebei Medicine

摘　　要：目的:探讨莫西沙星(MXFX)联合阿奇霉素治疗支原体肺炎的有效性和安全性。方法:将2007年1月至2008年1月间在我院住院治疗的82例支原体肺炎患者随机分为治疗组和对照组,两组均给予阿奇霉素治疗,治疗组同时给予莫西沙星。结果:治疗组在体温恢复时间、咳嗽消失时间、肺部罗音消失时间及细菌转阴率方面与对照组比较差异具有统计学意义(P<0.05)。治疗组总有效率为90.48%,对照组总有效率78.57%,两者比较差异具有统计学意义(P<0.05)。治疗组和对照组药物不良反应发生率均为4.76%,两组比较差异无统计学意义(P>0.05)。两组不良反应轻微,均未影响治疗。结论:莫西沙星联合阿奇霉素治疗支原体肺炎较单一用药效果好,无毒副作用,值得推广应用。Objective： To investigate the effect and safety of moxifloxacin combined with azithromycin in treating mycoplasma pneumonia.Method： 82 patients with mycoplasma pneumonia in our hospital from Jan.in 2007 to Jan.in 2008 were divided into the treatment group（42 cases） and control group（42 cases）.The patients in two groups were given azithromycin,and in the meanwhile those in treatment group were given moxifloxacin.Result： There was significant difference between two groups about the time of body temperature recovering,cough dispearing,bellows rales dispearing and rate of bacterium dispearing after treatment（P0.05）.The total effective rate was 90.48% respectively in the treatment group and control group 78.57%,and there was significant difference between them（P0.05）.The rate of drug adverse reaction was both 4.76%in the treatment group and in the control group,and there was no significant difference between them（P0.05）.There was little drug adverse reaction.Conclusion： The effect of moxifloxacin combined with azithromycin in treating mycoplasma pneumonia is obvious and the side effect is few,so it is worth being used widely.

关 键 词：莫西沙星 阿奇霉素 支原体肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]