毛细管电泳表征巯基聚乙二醇与碲化镉量子点相互作用  

Study on the Interaction of CdTe Quantum Dots with Thiol-polyethylene Glycol by Capillary Electrophoresis

作　　者：王晏睿[1] 黄香宜[1] 董朝青[1] 任吉存[1] 

机构地区：[1]上海交通大学化学化工学院,上海200240

出　　处：《分析科学学报》2010年第2期175-178,共4页Journal of Analytical Science

基　　金：科技部863专项(No.2006AA03Z324);国家自然科学基金(No.20705019)

摘　　要：本文采用毛细管电泳和荧光光谱法,研究了水相合成的碲化镉量子点与巯基聚乙二醇配体相互作用。研究发现巯基聚乙二醇能够包覆在碲化镉量子点表面。这种包覆层能够提高量子点的稳定性和生物相容性。In this paper,we systematically investigated the interaction between CdTe QDs and thiol-polyethylene glycol （PEG-SH） using capillary electrophoresis （CE） and fluorescence spectrometry. We found that PEG-SH was able to bind to CdTe QDs and form QDs-PEG-SH conjugates. The QDs-PEG-SH conjugates were well separated from QDs and PEG-SH reaction mixture by CE. The data demonstrated that PEG-SH possessed strong adsorption to QDs,and QDs-PEG-SH conjugates had showed good stability and fluorescent property,and had potential applications in biological and biomedical fields. Moreover,it also illustrated that CE was a useful tool to study the interaction of QDs with ligand molecules.

关 键 词：毛细管电泳 巯基聚乙二醇 碲化镉量子点 相互作用 

分 类 号：O657.8[理学—分析化学]