宁夏回族自治区0-14岁健康儿童脊灰抗体水平监测  

Monitoring of immune level of poliomyelitis in healthy children in Ningxia

作　　者：陈阿丽[1] 李丽[1] 刘天锡 詹军[1] 

机构地区：[1]宁夏自治区疾病预防控制中心,宁夏银川750004 [2]宁夏自治区卫生厅,宁夏银川750001

出　　处：《宁夏医学杂志》2010年第4期351-352,共2页Ningxia Medical Journal

摘　　要：目的了解宁夏0-14岁健康儿童脊灰抗体水平,为及时制定免疫策略提供科学依据。方法采用随机抽样的方法抽取银川、中卫、固原市0-14岁健康儿童403名,运用酶联免疫吸附试验(ELISA)检测脊灰IgG抗体。结果0-14岁儿童脊灰抗体阳性率为99.0%,抗体阳性保护率为94.8%,抗体脊灰平均滴度为1∶1567。不同地区儿童脊灰抗体平均滴度和保护率均不同;不同年龄段、不同免疫史儿童脊灰抗体保护率有差异,滴度呈递增趋势。结论0-14岁健康儿童脊灰抗体阳性率和几何平均滴度均保持在较高水平,已经成了牢固的免疫屏障。Objective To understand the immune status of poliomyelitis among 0-14 healthy children in Ningxia,and to provide scientific evidence for the immunization strategy.Methods 0-14 year-old healthy children were randomly enrolled from Yinchuan,Zhongwei,and Guyuan.The enzyme-linked immunosorbent assay（ELISA） was used for detecting IgG antibodies.Results The positive rate of polio serum IgG antibody was 99.0%,and there was 94.8% cases of polio antibody level reached the level of protection in 403 healthy children.Geometric mean antibody titer（GMT） was 1：1567.The average children＇s polio antibody titers and protection rates were different in different area;the different ages and different history of children＇s polio immune body protection ration were different,the antibody titer increased progressively.Conclusion IgG antibody positive rate and GMT level are still maintaining a high leave,and the firm immune barrier to poliomyelitis between 0-14 had been formed.

关 键 词：脊髓灰质炎 抗体 监测 

分 类 号：R181.3[医药卫生—流行病学] R725.1[医药卫生—公共卫生与预防医学]