矽肺患者肺功能分析  

Study on Pulmonary Function of 57 Patients With Silicosis

作　　者：乜庆荣[1] 张爱民[1] 李继平[1] 韩雪峰[1] 邓赶飞[1] 

机构地区：[1]北京市房山区良乡医院呼吸科,北京房山102401

出　　处：《职业卫生与病伤》2010年第2期96-97,共2页Occupational Health and Damage

摘　　要：目的探讨矽肺患者肺功能受损情况。方法对57例矽肺患者最大肺活量(VCmax),用力肺活量(FVC),1秒时间用力呼出量(FEV1),1秒时间用力呼出量与用力肺活量之比(FEV1/FVC),最大呼气中期流速(MMEF),25%、50%、75%肺量时的最大呼气流量(V25、V50、V75),肺总量(TLC),残气量(RV),残总比(RV/TLC),肺弥散量(DLCO)等肺功能指标进行测定分析。结果Ⅰ期与Ⅱ期矽肺患者肺功能损伤以混合型为主,且Ⅰ期矽肺患者FEV1%、FEV1/FVC、V25、V50、MMEF测定值与Ⅱ期矽肺患者比较,差异有统计学意义(P<0.05)。结论矽肺患者肺功能损伤明显,且随矽肺期别增加而加重,损伤类型以混合为主。Ⅱ期矽肺患者大、小气道的阻塞较Ⅰ期矽肺病人加重。Objective To explore the damage of pulmonary function of silicosis patients. Methods The pulmo- nary function examination was conducted among 57 male silicosis patients. The indicators of lung function in- eluded VC （vital capacity）, FVC （forced vital capacity）, FEV1 （the first second forced expiratory volume）, MMEF（ maximal midexpiratory flow rate）, V50 （maximal expiratory flow in fifty percent vital capacity） and V25 （maximal expiratory flow in twenty five percent vital capacity）. Results The damage types were mainly mixed ones among the silicosis patients. The lung function of silicosis patients at stage Ⅱ was obviously lower than that of those at stage I in FEV1%, FEV1/FVC, V25, V50 and MMEF. Conclusion The pulmonary function of the silicosis patients was damaged obviously, which increased with the stage of silicosis, and the types of the damage were mainly mixed ones. Compared with stage I, the big airway and small airway obstruc- tions of silicosis patients at stage II were more severe.

关 键 词：矽肺 肺功能 损伤 

分 类 号：R135.2[医药卫生—劳动卫生]